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Gene ontology
Version 2014-12-22
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Details for carbonyl reductase (NADPH) activity
1.1.1.184
Gene ontology ID
GO:0004090
Definition
Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+
Synonyms
1. aldehyde reductase 1
2. aldehyde reductase I activity
3. ALR3
4. carbonyl reductase activity
5. NADPH-dependent carbonyl reductase activity
6. NADPH2-dependent carbonyl reductase activity
7. nonspecific NADPH-dependent carbonyl reductase activity
8. prostaglandin 9-ketoreductase activity
9. secondary-alcohol:NADP+ oxidoreductase activity
10. xenobiotic ketone reductase activity
References
1. EC 1.1.1.184
2. MetaCyc CARBONYL-REDUCTASE-NADPH-RXN
3. Reactome: R-HSA-8937419 "CBR3 reduces DOX to DOXOL"
4. RHEA: 19257
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