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Gene ontology
Version 2014-12-22
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Details for monooxygenase activity
Gene ontology ID
GO:0004497
Definition
Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water
Synonyms
1. hydroxylase activity
References
1. ISBN 0198506732
2. Reactome: R-HSA-143468 "MEOS oxidizes ethanol to acetaldehyde"
3. Reactome: R-HSA-156526 "CYP1A2,3A4,3A5,2A13 oxidise AFB1 to AFXBO"
4. Reactome: R-HSA-211882 "CYP3A7 can 6beta-hydroxylate testosterone"
5. Reactome: R-HSA-211904 "CYP4F12 18-hydroxylates ARA"
6. Reactome: R-HSA-211910 "CYP2C8 inactivates paclitaxel by 6alpha-hydroxylation"
7. Reactome: R-HSA-211919 "CYP4F8 19-hydroxylates PGH2"
8. Reactome: R-HSA-211924 "CYP4B1 12-hydroxylates ARA"
9. Reactome: R-HSA-211929 "CYP2C19 5-hydroxylates omeprazole"
10. Reactome: R-HSA-211948 "CYP3A4 can N-demethylate loperamide"
11. Reactome: R-HSA-211951 "CYP1B1 4-hydroxylates EST17b"
12. Reactome: R-HSA-211959 "CYP3A43 6b-hydroxylates TEST"
13. Reactome: R-HSA-211960 "CYP2U1 19-hydroxylates ARA"
14. Reactome: R-HSA-211962 "CYP4F11 16-hydroxylates 3OH-PALM"
15. Reactome: R-HSA-211968 "CYP2W1 oxidises INDOL"
16. Reactome: R-HSA-211988 "CYP2C9 inactivates tolbutamide by 4methyl-hydroxylation"
17. Reactome: R-HSA-211991 "Cyclophosphamide is 4-hydroxylated by CYP2B6"
18. Reactome: R-HSA-212004 "CYP2C18 initiates bioactivation of phenytoin by 4-hydroxylation"
19. Reactome: R-HSA-212005 "CYP2F1 dehydrogenates 3-methylindole"
20. Reactome: R-HSA-213175 "CYP3A4,5 oxidise AFB1 to AFXBO"
21. Reactome: R-HSA-215526 "CYP4F3 20-hydroxylates LTB4"
22. Reactome: R-HSA-2161795 "Arachidonic acid is hydroxylated to 16/17/18-HETE by CYP(1)"
23. Reactome: R-HSA-2161814 "Arachidonic acid is hydroxylated to 19-HETE by CYP(2)"
24. Reactome: R-HSA-2161890 "Arachidonic acid is epoxidated to 5,6-EET by CYP(4)"
25. Reactome: R-HSA-2161899 "Arachidonic acid is epoxidated to 8,9/11,12/14,15-EET by CYP(5)"
26. Reactome: R-HSA-2161940 "Arachidonic acid is hydroxylated to 20-HETE by CYP(3)"
27. Reactome: R-HSA-2162191 "DMPhOH is hydroxylated to MDMQ10H2 by DMPhOH monooxygenase"
28. Reactome: R-HSA-217258 "FMO2:FAD:Mg2+ S-oxidises MTZ"
29. Reactome: R-HSA-5423647 "CYP2A13 oxidises AFM1 to AFM1E"
30. Reactome: R-HSA-5423664 "CYP3A4,5 hydroxylates AFB1 to AFQ1"
31. Reactome: R-HSA-5423672 "CYP1A2, 3A4 oxidise AFB1 to AFNBO"
32. Reactome: R-HSA-5423678 "CYP1A2 hydroxylates AFB1 to AFM1"
33. Reactome: R-HSA-5602242 "Defective CYP2U1 does not omega-hydroxylate ARA"
34. Reactome: R-HSA-5602272 "Defective CYP4F22 does not 20-hydroxylate TrXA3"
35. Reactome: R-HSA-5602295 "CYP4F22 20-hydroxylates TrXA3"
36. Reactome: R-HSA-5605147 "Defective CYP1B1 does not 4-hydroxylate EST17b"
37. Reactome: R-HSA-5662662 "Tyrosinase oxidises tyrosine to dopaquinone"
38. Reactome: R-HSA-5662692 "Dopa is oxidized to dopaquinone by TYR"
39. Reactome: R-HSA-5663050 "DHI and DHICA polymerise forming eumelanin"
40. Reactome: R-HSA-6786239 "CYP4V2 omega-hydroxylates DHA to HDoHE"
41. Reactome: R-HSA-76354 "Vinyl chloride is oxidized to 2-Chloroethylene oxide"
42. Reactome: R-HSA-76373 "N-hydroxylation of 4-aminobiphenyl"
43. Reactome: R-HSA-76386 "CYP1A2 S-demethylates 6MMP"
44. Reactome: R-HSA-76397 "Acetaminophen oxidised to N-acetylbenzoquinoneimine (NAPQI)"
45. Reactome: R-HSA-76416 "Benzene is hydroxylated to phenol"
46. Reactome: R-HSA-76426 "N-atom dealkylation of caffeine"
47. Reactome: R-HSA-76434 "Dehalogenation of carbon tetrachloride to form a free radical"
48. Reactome: R-HSA-76456 "O-atom dealkylation of dextromethorphan"
49. Reactome: R-HSA-76466 "CYP4A11 12-hydroxylates DDCX"
50. Reactome: R-HSA-76472 "Ethylene is oxidized to Ethylene oxide by CYP1A1"
51. Reactome: R-HSA-76475 "Dehalogenation of the poly-halogenated hydrocarbon Halothane to form the acylhalide Trifluoroacetlychloride and hydrogen bromide"
52. Reactome: R-HSA-8865107 "MICAL1 produces NADP+, H2O2"
53. Reactome: R-HSA-9018874 "CYP monooxygenates EPA to 18(S)-HpEPE"
54. Reactome: R-HSA-9027042 "CPY4 -oxidises 14(S)-HDHA to MaR-L1"
55. Reactome: R-HSA-9027043 "CYPs hydroxylate DHA to 14(R)-HDHA"
56. Reactome: R-HSA-9027044 "CYP4 -oxidises 14(R)-HDHA to MaR-L2"
57. Reactome: R-HSA-9027302 "CYP2E1 oxidises 14(S)-HDHA to 14(S),21(R)-diHDHA and 14(S),21(S)-diHDHA"
58. Reactome: R-HSA-9027321 "CYP2E1 oxidises 14(R)-HDHA to 14(R),21(R)-diHDHA and 14(R),21(S)-diHDHA"
59. Reactome: R-HSA-9037761 "CYP1, CYP2 hydroxylate (N)PD1 to 22-OH-(N)PD1"
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