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Gene ontology
Version 2014-12-22
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Details for L-iditol 2-dehydrogenase activity
1.1.1.14
Gene ontology ID
GO:0003939
Definition
Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+
Comment
Note that enzymes with this activity also act on D-glucitol (giving D-fructose) and other closely related sugar alcohols.
Synonyms
1. glucitol dehydrogenase activity
2. L-iditol (sorbitol) dehydrogenase activity
3. L-iditol:NAD oxidoreductase activity
4. L-iditol:NAD+ 5-oxidoreductase activity
5. NAD+-dependent sorbitol dehydrogenase activity
6. NAD-dependent sorbitol dehydrogenase activity
7. NAD-sorbitol dehydrogenase
8. polyol dehydrogenase activity
9. sorbitol dehydrogenase activity
References
1. EC 1.1.1.14
2. MetaCyc L-IDITOL-2-DEHYDROGENASE-RXN
3. Reactome: R-HSA-5652195 "SORD oxidizes D-sorbitol to Fru"
4. RHEA: 10160
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