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Ontology explorer

Gene ontology
Version 2014-12-22
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Details for homoisocitrate dehydrogenase activity
1.1.1.155, 1.1.1.87
Gene ontology ID
GO:0047046
Definition
Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate
Comment
Note that EC:1.1.1.155 was merged into EC:1.1.1.87 as they are identical.
Synonyms
1. (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD(+) oxidoreductase (decarboxylating) activity
2. (-)-1-hydroxy-1,2,4-butanetricarboxylate:NAD+ oxidoreductase (decarboxylating)
3. (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate:NAD+ oxidoreductase (decarboxylating)
4. 2-hydroxy-3-carboxyadipate dehydrogenase activity
5. 3-carboxy-2-hydroxyadipate dehydrogenase activity
6. 3-carboxy-2-hydroxyadipate:NAD(+) oxidoreductase (decarboxylating) activity
7. 3-carboxy-2-hydroxyadipate:NAD+ oxidoreductase (decarboxylating)
8. homoisocitric dehydrogenase activity
References
1. EC 1.1.1.155
2. EC 1.1.1.87
3. MetaCyc 1.1.1.87-RXN
4. RHEA: 11900
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// tissue/ enzyme/ localization link to BRENDA
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