Reference on EC 5.1.3.17 - heparosan-N-sulfate-glucuronate 5-epimerase and Organism(s) Homo sapiens and UniProt Accession O94923
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AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Tiedemann, K.; Larsson, T.; Heinegard, D.; Malmstrom, A.
The glucuronyl C5-epimerase activity is the limiting factor in the dermatan sulfate biosynthesis
Arch. Biochem. Biophys.
391
65-71
2001
Homo sapiens
Ghiselli, G.; Agrawal, A.
The human D-glucuronyl C5-epimerase gene is transcriptionally activated through the beta-catenin-TCF4 pathway
Biochem. J.
390
493-499
2005
Homo sapiens (O94923), Homo sapiens
Hagner-McWhirter, A.; Li, J.P.; Oscarson, S.; Lindahl, U.
Irreversible glucuronyl C5-epimerization in the biosynthesis of heparan sulfate
J. Biol. Chem.
279
14631-14638
2004
Homo sapiens
Grigorieva, E.; Eshchenko, T.; Rykova, V.I.; Chernakov, A.; Zabarovsky, E.; Sidorov, S.V.
Decreased expression of human D-glucuronyl C5-epimerase in breast cancer
Int. J. Cancer
122
1172-1176
2008
Homo sapiens
Li, K.; Bethea, H.N.; Liu, J.
Using engineered 2-O-sulfotransferase to determine the activity of heparan sulfate C5-epimerase and its mutants
J. Biol. Chem.
285
11106-11113
2010
Homo sapiens
Grigorieva, E.; Prudnikova, T.; Domanitskaya, N.; Mostovich, L.; Pavlova, T.; Kashuba, V.; Zabarovsky, E.
D-Glucuronyl C5-epimerase suppresses small-cell lung cancer cell proliferation in vitro and tumour growth in vivo
Br. J. Cancer
105
74-82
2011
Homo sapiens (O94923), Homo sapiens
Prudnikova, T.Y.; Soulitzis, N.; Kutsenko, O.S.; Mostovich, L.A.; Haraldson, K.; Ernberg, I.; Kashuba, V.I.; Spandidos, D.A.; Zabarovsky, E.R.; Grigorieva, E.V.
Heterogeneity of D-glucuronyl C5-epimerase expression and epigenetic regulation in prostate cancer
Cancer Med.
2
654-661
2013
Homo sapiens
Sheng, J.; Xu, Y.; Dulaney, S.B.; Huang, X.; Liu, J.
Uncovering biphasic catalytic mode of C5-epimerase in heparan sulfate biosynthesis
J. Biol. Chem.
287
20996-21002
2012
Homo sapiens
Zhang, J.; Suflita, M.; Li, G.; Zhong, W.; Li, L.; Dordick, J.S.; Linhardt, R.J.; Zhang, F.
High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin
Appl. Biochem. Biotechnol.
175
2986-2995
2015
Homo sapiens (O94923)
Babu, P.; Victor, X.V.; Raman, K.; Kuberan, B.
A rapid, nonradioactive assay for measuring heparan sulfate C-5 epimerase activity using hydrogen/deuterium exchange-mass spectrometry
Methods Mol. Biol.
1229
209-219
2015
Homo sapiens (O94923), Homo sapiens
Rosenberg, E.; Prudnikova, T.; Zabarovsky, E.; Kashuba, V.; Grigorieva, E.
D-Glucuronyl C5-epimerase cell type specifically affects angiogenesis pathway in different prostate cancer cells
Tumor Biol.
35
3237-3245
2014
Homo sapiens (O94923)
Ushakov, V.; Tsidulko, A.; De La Bourdonnaye, G.; Kazanskaya, G.; Volkov, A.; Kiselev, R.; Kobozev, V.; Kostromskaya, D.; Gaytan, A.; Krivoshapkin, A.; Aidagulova, S.; Grigorieva, E.
Heparan sulfate biosynthetic system is inhibited in human glioma due to EXT1/2 and HS6ST1/2 down-regulation
Int. J. Mol. Sci.
18
2301
2017
Homo sapiens (O94923)
