Reference on EC 3.4.24.B15 - PHEX peptidase and Organism(s) Mus musculus and UniProt Accession P70669
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Boeckmann, B.; Bairoch, A.; Apweiler, R.; Blatter, M.C.; Estreicher, A.; Gasteiger, E.; Martin M.J.; Michoud, K.; O'Donovan, C.; Phan, I.; Pilbout, S.; Schneider, M.
The SWISS-PROT protein knowledgebase and its supplement TrEMBL
Nucleic Acids Res.
31
365-370
2003
Homo sapiens (P78562), Mus musculus (P70669)
Guo, R.; Liu, S.; Spurney, R.F.; Quarles, L.D.
Analysis of recombinant Phex: an endopeptidase in search of a substrate
Am. J. Physiol.
281
E837-847
2001
Homo sapiens, Mus musculus
Guo, R.; Rowe, P.S.; Liu, S.; Simpson, L.G.; Xiao, Z.S.; Darryl Quarles, L.D.
Inhibition of MEPE cleavage by Phex
Biochem. Biophys. Res. Commun.
297
38-45
2002
Mus musculus
Alos, N.; Ecarot, B.
Downregulation of osteoblast Phex expression by PTH
Bone
37
589-598
2005
Mus musculus, Mus musculus C57/BL6J
Erben, R.G.; Mayer, D.; Weber, K.; Jonsson, K.; Jueppner, H.; Lanske, B.
Overexpression of human PHEX under the human beta-actin promoter does not fully rescue the Hyp mouse phenotype
J. Bone Miner. Res.
20
1149-1160
2005
Homo sapiens, Mus musculus
Yuan, B.; Takaiwa, M.; Clemens, T.L.; Feng, J.Q.; Kumar, R.; Rowe, P.S.; Xie, Y.; Drezner, M.K.
Aberrant Phex function in osteoblasts and osteocytes alone underlies murine X-linked hypophosphatemia
J. Clin. Invest.
118
722-734
2008
Mus musculus
Boskey, A.; Frank, A.; Fujimoto, Y.; Spevak, L.; Verdelis, K.; Ellis, B.; Troiano, N.; Philbrick, W.; Carpenter, T.
The PHEX transgene corrects mineralization defects in 9-month-old hypophosphatemic mice
Calcif. Tissue Int.
84
126-137
2009
Mus musculus (P70669)
Guo, R.; Quarles, L.D.
Cloning and sequencing of human PEX from a bone cDNA library: evidence for its developmental stage-specific regulation in osteoblasts
J. Bone Miner. Res.
12
1009-1017
1997
Homo sapiens (P78562), Mus musculus (P70669)
David, V.; Martin, A.; Hedge, A.M.; Drezner, M.K.; Rowe, P.S.
ASARM peptides: PHEX-dependent and -independent regulation of serum phosphate
Am. J. Physiol. Renal Physiol.
300
F783-F791
2011
Mus musculus
Martin, A.; Liu, S.; David, V.; Li, H.; Karydis, A.; Feng, J.Q.; Quarles, L.D.
Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling
FASEB J.
25
2551-2562
2011
Mus musculus
Ichikawa, S.; Austin, A.; Gray, A.; Econs, M.
A Phex mutation in a murine model of X-linked hypophosphatemia alters phosphate responsiveness of bone cells
J. Bone Miner. Res.
27
453-460
2012
Mus musculus (P70669)