Information on EC 2.4.1.16 - chitin synthase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Specify your search results
Mark a special word or phrase in this record:
Select one or more organisms in this record:
Show additional data
Do not include text mining results
Include (text mining) results (more...)
Include results (AMENDA + additional results, but less precise; more...)


The expected taxonomic range for this enzyme is: Eukaryota

EC NUMBER
COMMENTARY
2.4.1.16
-
RECOMMENDED NAME
GeneOntology No.
chitin synthase
REACTION TYPE
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
hexosyl group transfer
-
-
-
-
PATHWAY
KEGG Link
MetaCyc Link
Amino sugar and nucleotide sugar metabolism
-
chitin biosynthesis
-
SYSTEMATIC NAME
IUBMB Comments
UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase
Converts UDP-N-acetyl-alpha-D-glucosamine into chitin and UDP.
SYNONYMS
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
AaCHS-1
Q9NHE6
-
acetylglucosaminyltransferase, chitin-uridine diphosphate
-
-
-
-
AgCHS-1
Q95UA6
-
CaChs2p
-
-
chitin synthase 1
P23316
-
chitin synthase 1
P30600
-
chitin synthase 1
Q4VJB8
-
chitin synthase 1
-
-
chitin synthase 1
Saccharomyces cerevisiae X2180
-
-
-
chitin synthase 1
P30598
-
chitin synthase 2
Q4VW80
-
chitin synthase 2
-
-
chitin synthase 2
Q5YCX0
-
chitin synthase 2
Q530Z6
-
chitin synthase 2
-
-
chitin synthase 2
-
-
chitin synthase 2
A6ZKY2
-
chitin synthase 2
Saccharomyces cerevisiae Y3437
A6ZKY2
-
-
chitin synthase 2
Saccharomyces cerevisiae YPH499
-
-
-
chitin synthase 2
P30599
-
chitin synthase 3
Q5KCU4
-
chitin synthase 3
P29465
-
chitin synthase 3
Q99126
-
chitin synthase 3a
-
-
chitin synthase 4
Q99127
-
chitin synthase 5
O13394
-
chitin synthase 6
O13395
-
chitin synthase 7
Q4P333
-
chitin synthase A
Q3I5Q4
-
chitin synthase B
Q06BR7
-
chitin synthase II
Q30LK7, Q30LS3
-
chitin synthase III
-
-
chitin synthase III
-
-
chitin synthase III
P29465
-
chitin synthase protein 2
-
-
chitin synthetase
-
-
-
-
chitin synthetase I
Kluyveromyces bulgaricus
-
-
chitin synthetase II
Kluyveromyces bulgaricus
-
-
chitin synthetase III
Kluyveromyces bulgaricus
-
-
chitin-UDP acetyl-glucosaminyl transferase 1
P30600
-
chitin-UDP acetyl-glucosaminyl transferase 1
P30598
-
chitin-UDP acetyl-glucosaminyl transferase 2
P30599
-
chitin-UDP acetyl-glucosaminyl transferase 3
Q99126
-
chitin-UDP acetyl-glucosaminyl transferase 4
Q99127
-
chitin-UDP acetyl-glucosaminyl transferase 5
O13394
-
chitin-UDP acetyl-glucosaminyl transferase 6
O13395
-
chitin-UDP acetyl-glucosaminyl transferase 7
Q4P333
-
chitin-UDP N-acetylglucosaminyltransferase
-
-
-
-
chitin-uridine diphosphate acetylglucosaminyltransferase
-
-
-
-
CHS
-, Q8TFN5, Q8TFN6
-
CHS
Q06BR7
-
CHS
Q3I5Q4
-
CHS
Q6WD22, Q6WD23
-
CHS B
Q06BR7
-
chs-1
Q4VJB8
-
chs-2
Q4VW80
-
CHS-3
P30588
-
CHS-3
Neurospora crassa N623
P30588
-
-
CHS-6
Neurospora crassa N623
-
-
-
Chs1
-
-
-
-
Chs1
P23316
-
Chs1
P30598
-
CHS1p
P23316
-
CHS1p
Saccharomyces cerevisiae YPH499
-
-
-
Chs2
-
-
-
-
Chs2
P30572
-
Chs2
Q530Z6
-
Chs2
Saccharomyces cerevisiae Y3437
A6ZKY2
-
-
Chs2
P30599
-
CHS2p
Saccharomyces cerevisiae YPH499
-
-
-
CHS3
P30573
-
CHS3
Q99126
-
Chs3p
Saccharomyces cerevisiae YPH499
-
-
-
CHS4
Q99127
-
CHS5
O13394
-
CHS6
O13395
-
CHS7
Q4P333
-
Chs8
Q5A7T2
-
Chs8
Q4P9K9
-
chsA
Q3I5Q4
-
chsB
Q00757
-
chsB
Q2V6H3
-
chsC
P30583
-
chsC
Q92197
-
chsE
P78611
-
class A chitin synthase
B4YIR0
-
class A chitin synthase
Q3I5Q4
-
class I CHS
P30588
-
class I CHS
Neurospora crassa N623
P30588
-
-
class IV CaChs3p
-
-
class IV chitin synthase
-
-
class IV CHS
-
-
class IV CHS
Neurospora crassa N623
-
-
-
class V chitin synthase
-
-
class V chitin synthase
Q8TGV2
-
class Vb chitin synthase
-
-
class VII chitin synthase
Q5YCX0
-
class-A CHS
Q6WD23
-
class-B CHS
Q6WD22
-
class-II chitin synthase 1
P30600
-
CSI
-
-
-
-
CSII
-
-
-
-
CSIII
-
-
-
-
CsmA
O13281
-
CsmB
Q2L6A0
-
LcCHS-1
Q9GU17
-
LeChs1
A0PAB0
-
LsCHS-1
Lucilia sp.
-
-
MsCHS-1
Q8T4U2
-
MsCHS1
Q8T4U2
-
MsCHS2
Q530Z6
-
myosin motor-like chitin synthase
Q5YCX0
-
trans-N-acetylglucosaminosylase
-
-
-
-
UDP-GlcNAc:chitin 4-alpha-N-acetylglucosaminyltransferase
-
-
UmCHS3
-
-
UmCHS6
-
-
WdCHS1
P30600
-
WdChs5p
Q8TGV2
-
Mcs1
Q4P9K9
-
additional information
Q5YCX0
ChsVb belongs to class VII chitin synthases
CAS REGISTRY NUMBER
COMMENTARY
9030-18-6
-
ORGANISM
COMMENTARY
LITERATURE
SEQUENCE CODE
SEQUENCE DB
SOURCE
Amylomyces rouxii IM-80
IM-80
-
-
Manually annotated by BRENDA team
Apodachlya sp.
-
-
-
Manually annotated by BRENDA team
Chs1; isozyme Chs1, gene CHS1
UniProt
Manually annotated by BRENDA team
Chs2; isozymeChs2, gene CHS2
UniProt
Manually annotated by BRENDA team
Chs3; isozyme Chs3, gene CHS3
UniProt
Manually annotated by BRENDA team
Chs8; isozyme Chs8, gene CHS8
UniProt
Manually annotated by BRENDA team
Chlorovirus CVK2
-
-
-
Manually annotated by BRENDA team
chitin synthase B
-
-
Manually annotated by BRENDA team
EhCHS-1; EhCHS-2
-
-
Manually annotated by BRENDA team
class 3 chitin synthase
-
-
Manually annotated by BRENDA team
i.e. Exophiala dermatitidis, strain 8656, ATCC 34100, isozyme WdChs5p
UniProt
Manually annotated by BRENDA team
isoform Chs5
UniProt
Manually annotated by BRENDA team
isoform CHS5; isoform Chs5
UniProt
Manually annotated by BRENDA team
isoform CHS1
-
-
Manually annotated by BRENDA team
chitin synthase 2; f. sp. lycopersici, myosin motor-like chitin synthase gene chsVb
UniProt
Manually annotated by BRENDA team
isoform CHS5
UniProt
Manually annotated by BRENDA team
isoform Chs7
UniProt
Manually annotated by BRENDA team
strain GZ03643
-
-
Manually annotated by BRENDA team
Gibberella zeae GZ03643
strain GZ03643
-
-
Manually annotated by BRENDA team
CHSI; isozye CHS I
UniProt
Manually annotated by BRENDA team
CHSIII; isozyme CHS III
UniProt
Manually annotated by BRENDA team
the fungus contains 10 chitin synthase isozymes of different classes, overview
-
-
Manually annotated by BRENDA team
Kluyveromyces bulgaricus
ATCC 96631
-
-
Manually annotated by BRENDA team
LeChs1; an edible basidiomycetous mushroom, strain strain SB1226, gene Lechs1, isozyme LeChs1
UniProt
Manually annotated by BRENDA team
Lucilia sp.
-
-
-
Manually annotated by BRENDA team
isoform Chs7; isoform CHS7
UniProt
Manually annotated by BRENDA team
isoform CHS2
-
-
Manually annotated by BRENDA team
MsCHS2
SwissProt
Manually annotated by BRENDA team
Mortierella candelabrum
-
-
-
Manually annotated by BRENDA team
Mortierella pusilla
-
-
-
Manually annotated by BRENDA team
chs-6 gene; strain N623, isozyme CHS-6
-
-
Manually annotated by BRENDA team
isozyme CHS-3; strain N623, isozyme CHS-3
GenBank
Manually annotated by BRENDA team
slime mutant
-
-
Manually annotated by BRENDA team
wall-less variant
-
-
Manually annotated by BRENDA team
Neurospora crassa N623
chs-6 gene; strain N623, isozyme CHS-6
-
-
Manually annotated by BRENDA team
Neurospora crassa N623
isozyme CHS-3; strain N623, isozyme CHS-3
GenBank
Manually annotated by BRENDA team
fragment
SwissProt
Manually annotated by BRENDA team
isoform CHSA
B4YIR0
UniProt
Manually annotated by BRENDA team
gene chs2, fragment; gene chs2
UniProt
Manually annotated by BRENDA team
isoform Chs3; isoform Chs3
UniProt
Manually annotated by BRENDA team
an edible basidiomycetous mushroom, class IV chitin synthase isozyme, gene Pochs1
-
-
Manually annotated by BRENDA team
isoform CHSIIIa, hypothetical
UniProt
Manually annotated by BRENDA team
isoform CHSIIIb, hypothetical
UniProt
Manually annotated by BRENDA team
chitin synthase 1 is examide in wild-type strain ATCC 26109 and D3C (MATalphaura3-52), chitin synthase 2 is investigated in a strain D3B freed of chitin synthase 1 by gene disruption; chitin synthetase 1 and 2
-
-
Manually annotated by BRENDA team
chitin synthase 1, 2 and 3
-
-
Manually annotated by BRENDA team
chitin synthase 2; strains ECY38-38A and YPH499
UniProt
Manually annotated by BRENDA team
chitin synthetase 1 and 2
-
-
Manually annotated by BRENDA team
chitin synthetase 2
-
-
Manually annotated by BRENDA team
gene chs3coding for the catalytic subunit of the chitin synthase III
SwissProt
Manually annotated by BRENDA team
strain Y3437, isozyme Chs2
UniProt
Manually annotated by BRENDA team
strain YPH499 and ECY38-38A, isozyme CHS2p encoded by gene CHS2; strain YPH499 and ECY38-38A, isozymes CHS1p and CHS3p encoded by genes CHS1 and CHS3
-
-
Manually annotated by BRENDA team
strains ECY38-38A and YPH499
-
-
Manually annotated by BRENDA team
X2180 strains
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae X2180
X2180 strains
-
-
Manually annotated by BRENDA team
Saccharomyces cerevisiae Y3437
strain Y3437, isozyme Chs2
UniProt
Manually annotated by BRENDA team
Saccharomyces cerevisiae YPH499
strain YPH499 and ECY38-38A, isozyme CHS2p encoded by gene CHS2; strain YPH499 and ECY38-38A, isozymes CHS1p and CHS3p encoded by genes CHS1 and CHS3
-
-
Manually annotated by BRENDA team
isoform Chs1
UniProt
Manually annotated by BRENDA team
isoform Chs2
UniProt
Manually annotated by BRENDA team
chitin synthase A; gene A
UniProt
Manually annotated by BRENDA team
chitin synthase B; gene CHSB
UniProt
Manually annotated by BRENDA team
class A chitin synthase gene CHSA
UniProt
Manually annotated by BRENDA team
class-A CHS; red flour beetle, gene TcCHS-A
UniProt
Manually annotated by BRENDA team
class-B CHS; red flour beetle, gene TcCHS-B
UniProt
Manually annotated by BRENDA team
isoform Mcs1, class V chitin synthase
UniProt
Manually annotated by BRENDA team
pH RANGE
pH RANGE MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
5.5
8
-
pH 5.5: 40% of maximal activity, pH 8.0: 95% of maximal activity
6.5
8.5
-
pH 6.5: about 85% of maximal activity, pH 8.5: about 70% of maximal activity
7.1
8.3
-
50% of maximal activity at pH 7.1 and pH 8.3
TEMPERATURE STABILITY
TEMPERATURE STABILITY MAXIMUM
ORGANISM
UNIPROT ACCESSION NO.
COMMENTARY
LITERATURE
4
-
-
rapid decrease in activity within 5 h
4
-
-
gradual decrease in activity with time
25
-
-
2 h, solubilized preparations retain 80% of its activity
40
50
-
5 min, 20-25% loss of activity
60
-
-
5 min, complete loss of activity
additional information
-
Mortierella candelabrum
-
-
additional information
-
Mortierella pusilla
-
activity increases during low temperature storage