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Literature summary for 2.4.1.16 extracted from
- Properties of chitin synthase from mucoraceous hosts of a mycoparasite (1985), Can. J. Microbiol., 31, 6-12.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| NH4+ | slight increase in activity | Choanephora cucurbitarum |  |
| NH4+ | slight increase in activity | Phascolomyces articulosus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Fe3+ | - |
Choanephora cucurbitarum | |
| Fe3+ | - |
Phascolomyces articulosus | |
| Polyoxin D | - |
Choanephora cucurbitarum | |
| Polyoxin D | - |
Phascolomyces articulosus | |
| Zn2+ | - |
Choanephora cucurbitarum | |
| Zn2+ | - |
Phascolomyces articulosus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | the enzyme is mainly associated with the mixed membrane fraction | Choanephora cucurbitarum | - |
- |
| additional information | the enzyme is mainly associated with the mixed membrane fraction | Phascolomyces articulosus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | slight increase in activity | Choanephora cucurbitarum | |
| Ca2+ | slight increase in activity | Phascolomyces articulosus | |
| Co2+ | significant stimulation | Choanephora cucurbitarum | |
| Co2+ | significant stimulation | Phascolomyces articulosus | |
| K+ | slight increase in activity | Choanephora cucurbitarum | |
| K+ | slight increase in activity | Phascolomyces articulosus | |
| Mg2+ | stimulates | Choanephora cucurbitarum | |
| Mg2+ | stimulates | Phascolomyces articulosus | |
| Mn2+ | significant stimulation | Choanephora cucurbitarum | |
| Mn2+ | significant stimulation | Phascolomyces articulosus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Choanephora cucurbitarum | - |
- |
- |
| Phascolomyces articulosus | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | - |
Phascolomyces articulosus |
| proteolytic modification | activated by acid proteases, slightly activated by trypsin, inhibited by neutral proteases | Choanephora cucurbitarum |
| proteolytic modification | activated by all proteases | Choanephora cucurbitarum |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hypha | - |
Choanephora cucurbitarum | - |
| hypha | - |
Phascolomyces articulosus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Choanephora cucurbitarum | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | chitin | ? | |
| UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n | - |
Phascolomyces articulosus | UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1 | chitin | ? | |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 4 | - |
rapid decrease in activity within 5 h | Choanephora cucurbitarum |
| 4 | - |
gradual decrease in activity with time | Phascolomyces articulosus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.2 | - |
- |
Choanephora cucurbitarum |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.7 | - |
Polyoxin D | - |
Choanephora cucurbitarum | |
| 2.5 | - |
Polyoxin D | - |
Phascolomyces articulosus | |
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Release 2023.1 (January 2023)
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