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Literature summary for 2.4.1.16 extracted from

  • Plant, A.; Thompson, P.; Williams, D.M.
    Stereoselective synthesis of novel uracil polyoxin C conjugates as substrate analogues of chitin synthase (2008), J. Org. Chem., 73, 3714-3724.
    View publication on PubMed

Application

Application Comment Organism
agriculture enzyme inhibitors can be useful as potential pesticidal agents Saccharomyces cerevisiae
agriculture enzyme inhibitors can be useful as potential pesticidal agents Candida albicans

Inhibitors

Inhibitors Comment Organism Structure
nikkomycin Z
-
Candida albicans
nikkomycin Z
-
Saccharomyces cerevisiae
Polyoxin D
-
Candida albicans
Polyoxin D
-
Saccharomyces cerevisiae
polyoxin L
-
Candida albicans
polyoxin L
-
Saccharomyces cerevisiae
uracil polyoxin C methyl ester stereoselective synthesis routes of both the natural (C5'-S) and unnatural (C5'-R) diastereoisomers of uracil polyoxin C methyl ester as specific substrate analogue-inhibitors of chirin synthase, conjugation of the methyl ester of uracil polyoxin C with activated isoxazole carboxylic acids, detailed overview Candida albicans
uracil polyoxin C methyl ester stereoselective synthesis routes of both the natural (C5'-S) and unnatural (C5'-R) diastereoisomers of uracil polyoxin C methyl ester as specific substrate analogue-inhibitors of chirin synthase, conjugation of the methyl ester of uracil polyoxin C with activated isoxazole carboxylic acids, detailed overview Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Candida albicans
-
-
-
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-N-acetyl-D-glucosamine + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n
-
Saccharomyces cerevisiae UDP + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n+1
-
?
UDP-N-acetyl-D-glucosamine + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n
-
Candida albicans UDP + [(1-4)-N-acetyl-beta-D-glucosaminyl-]n+1
-
?