6.3.4.22: tRNAIle2-agmatinylcytidine synthase

This is an abbreviated version!
For detailed information about tRNAIle2-agmatinylcytidine synthase, go to the full flat file.

Reaction

+ 2 phosphate

Synonyms

AF2259, TiaS, tRNAIle-2-agmatinylcytidine synthetase, tRNAIle-agm2C synthetase, tRNAIle-agmatidine synthetase

ECTree

6 Ligases

6.3 Forming carbon-nitrogen bonds

6.3.4 Other carbon-nitrogen ligases

6.3.4.22 tRNAIle2-agmatinylcytidine synthase

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Results	in table
1809	AA Sequence
3	Cloned(Commentary)
2	Crystallization (Commentary)
2	General Information
2	IC50 Value
2	Inhibitors
3	kcat/KM [mM/s]
3	KM Value [mM]
2	Metals/Ions
2	Natural Substrates/ Products (Substrates)
5	Organism
3	PDB ID
1	pH Optimum
1	Posttranslational Modification
28	Protein Variants
4	Purification (Commentary)
1	Reaction
5	Reference
4	Substrates and Products (Substrate)
16	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
3	Turnover Number [1/s]

Reference

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Reference on EC 6.3.4.22 - tRNAIle2-agmatinylcytidine synthase

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705848

Ikeuchi, Y.; Kimura, S.; Numata, T.; Nakamura, D.; Yokogawa, T.; Ogata, T.; Wada, T.; Suzuki, T.; Suzuki, T.

Agmatine-conjugated cytidine in a tRNA anticodon is essential for AUA decoding in archaea

Nat. Chem. Biol.

277-282

2010

Archaeoglobus fulgidus (O28025), Pyrococcus horikoshii (O59476)

20139989

718503

Osawa, T.; Inanaga, H.; Kimura, S.; Terasaka, N.; Suzuki, T.; Numata, T.

Crystallization and preliminary X-ray diffraction analysis of an archaeal tRNA-modification enzyme, TiaS, complexed with tRNA(Ile2) and ATP

Acta Crystallogr. Sect. F

1414-1416

2011

Archaeoglobus fulgidus (O28025)

22102245

720531

Terasaka, N.; Kimura, S.; Osawa, T.; Numata, T.; Suzuki, T.

Biogenesis of 2-agmatinylcytidine catalyzed by the dual protein and RNA kinase TiaS

Nat. Struct. Mol. Biol.

1268-1274

2011

Archaeoglobus fulgidus (O28025)

22002222

720532

Osawa, T.; Kimura, S.; Terasaka, N.; Inanaga, H.; Suzuki, T.; Numata, T.

Structural basis of tRNA agmatinylation essential for AUA codon decoding

Nat. Struct. Mol. Biol.

1275-1280

2011

Archaeoglobus fulgidus (O28025)

22002223