6.3.2.38: N2-citryl-N6-acetyl-N6-hydroxylysine synthase
This is an abbreviated version!
For detailed information about N2-citryl-N6-acetyl-N6-hydroxylysine synthase, go to the full flat file.
Reaction
Synonyms
aerD, EC 6.3.2.27, iuacA, iucA, Nalpha-citryl-Nepsilon-acetyl-Nepsilon-hydroxylysine synthase
ECTree
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Substrates Products
Substrates Products on EC 6.3.2.38 - N2-citryl-N6-acetyl-N6-hydroxylysine synthase
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REACTION DIAGRAM
2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
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no activity with beta-gamma-ATP
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-
?
2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
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no activity with beta-gamma-ATP
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-
?
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
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-
-
-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
-
-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
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the enzyme is involved in biosynthesis of aerobactin
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-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
-
-
-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium
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-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine
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-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
-
-
-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine
-
-
?
2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium
-
-
?