6.3.2.38: N2-citryl-N6-acetyl-N6-hydroxylysine synthase

This is an abbreviated version!
For detailed information about N2-citryl-N6-acetyl-N6-hydroxylysine synthase, go to the full flat file.

Reaction

2 ATP +

Synonyms

aerD, EC 6.3.2.27, iuacA, iucA, Nalpha-citryl-Nepsilon-acetyl-Nepsilon-hydroxylysine synthase

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.38 N2-citryl-N6-acetyl-N6-hydroxylysine synthase

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Results	in table
173	AA Sequence
1	CAS Registry Number
2	Inhibitors
1	Metals/Ions
2	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organism
5	Pathway
1	Purification (Commentary)
1	Reaction
7	Reference
12	Substrates and Products (Substrate)
6	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 6.3.2.38 - N2-citryl-N6-acetyl-N6-hydroxylysine synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

7 entries

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Escherichia coli

-

-

720473

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Escherichia coli

Q47316

-

486099

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Escherichia coli

-

the enzyme is involved in biosynthesis of aerobactin

719292

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Klebsiella aerogenes

-

-

492296

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Klebsiella aerogenes

-

the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium

719001

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Klebsiella aerogenes 62-1

-

-

492296

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Klebsiella aerogenes 62-1

-

the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium

719001

-

-

?