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6.3.2.35: D-alanine-D-serine ligase

This is an abbreviated version!
For detailed information about D-alanine-D-serine ligase, go to the full flat file.

Word Map on EC 6.3.2.35

Reaction

D-alanine
+
D-serine
+
ATP
=
D-alanyl-D-serine
+
ADP
+
phosphate

Synonyms

D-alanine:D-serine ligase, VanC2, vanC2/3, VanE, VanG, vanGCar, VanL

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.2 Acid—amino-acid ligases (peptide synthases)
                6.3.2.35 D-alanine-D-serine ligase

Substrates Products

Substrates Products on EC 6.3.2.35 - D-alanine-D-serine ligase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-alanine + D-2-aminobutanoate + ATP
D-alanyl-D-2-aminobutanoate + ADP + phosphate
show the reaction diagram
-
-
-
-
?
D-alanine + D-alanine + ATP
D-alanyl-D-alanine + ADP + phosphate
show the reaction diagram
-
formation of D-alanyl-D-serine is 400fold prefered over formation of D-alanyl-D-alanine
-
-
?
D-alanine + D-allo-threonine + ATP
D-alanyl-D-allo-threonine + ADP + phosphate
show the reaction diagram
-
-
-
-
?
D-alanine + D-asparagine + ATP
D-alanyl-D-asparagine + ADP + phosphate
show the reaction diagram
-
-
-
-
?
D-alanine + D-glutamine + ATP
D-alanyl-D-glutamine + ADP + phosphate
show the reaction diagram
-
-
-
-
?
D-alanine + D-homoserine + ATP
D-alanyl-D-homoserine + ADP + phosphate
show the reaction diagram
-
-
-
-
?
D-alanine + D-serine + ATP
D-alanyl-D-serine + ADP + phosphate
show the reaction diagram
D-alanine + D-threonine + ATP
D-alanyl-D-threonine + ADP + phosphate
show the reaction diagram
-
-
-
-
?
additional information
?
-
-
amino acid preference in decreasing order: D-Ser, D-Asn, D-Thr, D-Gln, D-homoserine, D-aminobutanoate, D-allo-Thr
-
-
?