6.3.2.24: tyrosine-arginine ligase

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For detailed information about tyrosine-arginine ligase, go to the full flat file.

Reaction

Synonyms

KTP synthetase, kyotorphin synthase, kyotorphin synthetase, kyotorphin-synthesizing enzyme, synthetase, kyotorphin, tyrosyl-arginine synthase, TyrRS

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.24 tyrosine-arginine ligase

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Results	in table
1	CAS Registry Number
2	Cloned(Commentary)
3	Cofactor
8	General Information
12	Inhibitors
14	KM Value [mM]
3	Localization
5	Metals/Ions
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
146	Organism
2	pH Optimum
2	pH Range
1	pI Value
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
31	Source Tissue
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
1	Subunits
16	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]

KM Value

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KM Value on EC 6.3.2.24 - tyrosine-arginine ligase

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KM VALUE [mM]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.18 - 0.294

ATP

2 entries

0.926 - 7.83

L-arginine

5 entries

0.0256 - 0.2

L-tyrosine

5 entries

0.442

MgCl2

Rattus norvegicus

-

37°C, pH 8.0

648947

additional information

additional information

Homo sapiens

-

Michaelis-Menten kinetics

745971

-

0.18

ATP

Rattus norvegicus

-

37°C, pH 8.0, enzyme from adrenal gland

648948

0.294

ATP

Rattus norvegicus

-

37°C, pH 8.0

648947

0.926

L-arginine

Rattus norvegicus

-

37°C, pH 8.0

648947

1.4

L-arginine

Homo sapiens

-

pH 7.4, 37°C

745971

1.4

L-arginine

Homo sapiens

-

pH 7.4, 37°C, recombinant His-tagged enzyme

745971

4.58

L-arginine

Rattus norvegicus

-

37°C, pH 8.0, enzyme from spinal cord

648948

7.83

L-arginine

Rattus norvegicus

-

37°C, pH 8.0, enzyme from adrenal gland

648948

0.0256

L-tyrosine

Rattus norvegicus

-

37°C, pH 8.0

648947

0.03

L-tyrosine

Rattus norvegicus

-

37°C, pH 8.0, enzyme from adrenal gland

648948

0.07

L-tyrosine

Rattus norvegicus

-

37°C, pH 8.0, enzyme from spinal cord

648948

0.2

L-tyrosine

Homo sapiens

-

pH 7.4, 37°C

745971

0.2

L-tyrosine

Homo sapiens

-

pH 7.4, 37°C, recombinant His-tagged enzyme

745971