6.3.2.24: tyrosine-arginine ligase

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For detailed information about tyrosine-arginine ligase, go to the full flat file.

Reaction

Synonyms

KTP synthetase, kyotorphin synthase, kyotorphin synthetase, kyotorphin-synthesizing enzyme, synthetase, kyotorphin, tyrosyl-arginine synthase, TyrRS

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.24 tyrosine-arginine ligase

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Results	in table
1	CAS Registry Number
2	Cloned(Commentary)
3	Cofactor
8	General Information
12	Inhibitors
14	KM Value [mM]
3	Localization
5	Metals/Ions
3	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
146	Organism
2	pH Optimum
2	pH Range
1	pI Value
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
31	Source Tissue
1	Specific Activity [micromol/min/mg]
24	Substrates and Products (Substrate)
1	Subunits
16	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]

Natural Substrates Products

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Natural Substrates Products on EC 6.3.2.24 - tyrosine-arginine ligase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

ATP + L-tyrosine + L-arginine

L-tyrosyl-L-arginine + AMP + diphosphate

Rattus norvegicus

-

involved in biosynthesis of kyotorphin in rat brain

648947

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-

?