6.3.2.11: carnosine synthase

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For detailed information about carnosine synthase, go to the full flat file.

Reaction

Synonyms

ATPGD1, carnosine synthase, Carnosine synthetase, Carnosine-anserine synthetase, Carnosine-homocarnosine synthetase, CARNS, CAS, CRNS1, HCarn-Carn synthetase, Homocarnosine-carnosine synthetase, Synthetase, carnosine

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.11 carnosine synthase

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2	Activating Compound
20	AA Sequence
1	CAS Registry Number
2	Cloned(Commentary)
5	Cofactor
32	Disease/ Diagnostics
1	General Information
3	General Stability
47	Inhibitors
21	kcat/KM [mM/s]
31	KM Value [mM]
4	Localization
10	Metals/Ions
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
30	Organism
6	Pathway
5	pH Optimum
1	pH Range
1	pH Stability
10	Purification (Commentary)
3	Reaction
3	Reaction Type
30	Reference
65	Source Tissue
2	Specific Activity [micromol/min/mg]
1	Storage Stability
85	Substrates and Products (Substrate)
3	Subunits
19	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]

General Information

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General Information on EC 6.3.2.11 - carnosine synthase

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GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

physiological function

Homo sapiens

A5YM72

histidine-containing dipeptides like carnosine and anserine have protective functions in both health and disease. Carnosine is synthesized by the enzyme carnosine synthase (CARNS), which is present in skeletal and heart muscle, as well as in certain regions in the brain and kidney

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