6.3.2.11: carnosine synthase
This is an abbreviated version!
For detailed information about carnosine synthase, go to the full flat file.
Word Map on EC 6.3.2.11
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6.3.2.11
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dipeptide
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olfactory
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bulb
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castration-resistant
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high-intensity
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histidine-containing
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carnosine-related
Reaction
+
+
=
+
+
Synonyms
ATPGD1, carnosine synthase, Carnosine synthetase, Carnosine-anserine synthetase, Carnosine-homocarnosine synthetase, CARNS, CAS, CRNS1, HCarn-Carn synthetase, Homocarnosine-carnosine synthetase, Synthetase, carnosine
ECTree
Inhibitors
Inhibitors on EC 6.3.2.11 - carnosine synthase
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1,10-Diaminodecane
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10 mM, 43% loss of activity
1,8-diaminooctane
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10 mM, 27% loss of activity
1-methylhistidine
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synthesis of carnosine
2-Aminoethylphosphonic acid
3-Aminopropane sulfonic acid
3-Aminopropanephosphonic acid
-
-
3-methylhistidine
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synthesis of carnosine
5-Aminopentanol
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10 mM, 11% loss of activity
6-Aminohexanol
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10 mM, 10% loss of activity
Aminoethanol
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10 mM, 17% loss of activity
chlorpromazine
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0.1 mM stimulates, 1 mM inhibits 45%
K+
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10-100 mM, weak inhibition
n-butylamine
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10 mM, 15% loss of activity
n-Hexylamine
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10 mM, 34% loss of activity
n-octylamine
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10 mM, 58% loss of activity
2-Aminoethylphosphonic acid
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weak
2-Aminoethylphosphonic acid
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weak
3-Aminopropane sulfonic acid
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competitive with respect to beta-Ala
3-Aminopropane sulfonic acid
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competitive with respect to beta-Ala
5-Aminopentanoate
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no inhibition
5-Aminopentanoate
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noncompetitive with respect to beta-Ala
iodoacetamide
-
-
Ni2+
-
-
O-Phosphoethanolamine
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weak
O-Phosphoethanolamine
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weak
PCMB
-
-
spermidine
-
-
spermidine
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mixed type with respect to beta-alanine