5.4.2.12: phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

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For detailed information about phosphoglycerate mutase (2,3-diphosphoglycerate-independent), go to the full flat file.

Word Map on EC 5.4.2.12

5.4.2.12

mutases

2-phosphoglycerate

ipgms

2,3-bisphosphoglycerate-independent

cofactor-dependent

2,3-bisphosphoglycerate

mexicana

brugia

malayi

phosphoenzyme

dikinase

flux-controlling

filariasis

medicine

drug development

Reaction

Synonyms

2,3-biphosphoglycerate-independent phosphoglycerate mutase, 2,3-diphosphoglycerate-independent phosphoglycerate mutase, 2,3BPG-independent PGAM, 3-phosphoglycerate mutase, apgM, co-factor-independent phosphoglycerate mutase, cofactor independent phosphoglycerate mutase, cofactor-independent phosphoglycerate mutase, cofactor-independent phosphoglycerate mutase 1, EC 2.7.5.3, EC 5.4.2.1, independent PGAM, independent PGM, iPGAM, iPGM, MJ0010, MJ1612, PGAM, PGM, PH0037, SSO0417

ECTree

5 Isomerases

5.4 Intramolecular transferases

5.4.2 Phosphotransferases (phosphomutases)

5.4.2.12 phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

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Results	in table
23	Activating Compound
32490	AA Sequence
3	Application
32	Cloned(Commentary)
31	Cofactor
11	Crystallization (Commentary)
5	General Information
2	General Stability
5	IC50 Value
84	Inhibitors
9	kcat/KM [mM/s]
51	KM Value [mM]
11	Localization
29	Metals/Ions
37	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
132	Organism
26	Pathway
19	PDB ID
25	pH Optimum
13	pH Range
5	pH Stability
5	pI Value
1	Posttranslational Modification
18	Protein Variants
42	Purification (Commentary)
2	Reaction
86	Reference
6	Renatured (Commentary)
18	Source Tissue
31	Specific Activity [micromol/min/mg]
6	Storage Stability
78	Substrates and Products (Substrate)
32	Subunits
66	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
5	Temperature Stability [°C]
19	Turnover Number [1/s]

Purification

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Purification on EC 5.4.2.12 - phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

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10 entries

amylose column chromatography

Wolbachia sp.

Q5GSN3

694538

HiTrap nickel chelating column chromatography and HiTrap Q column chromatography

2 entries

metal affinity Talon column chromatography

Leishmania mexicana

Q86N96

705169

Ni-NTA agarose column chromatography

2 entries

Ni-NTA bead chromatography

Leishmania donovani

748833

Ni-NTA column chromatography

Entamoeba histolytica

C4LTW4

748541

Ni-NTA Sepharose column chromatography and Superdex 200 gel filtration

Staphylococcus aureus

Q2G029

746646

partially purified

Saccharolobus solfataricus

Q980A0

651716

partialy purified

7 entries

recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3) by metal affinity chromatography and gel filtration

Trypanosoma brucei

Q9NG18

727472

recombinant His6-tagged enzyme from Escherichia coli strain C2566/T7 by nicke affinity chromatography, dialysis and anion exchange chromatography

Wolbachia sp.

716984

recombinant His6-tagged enzyme from Escherichia coli strain C2566/T7 by nickel affinity chromatography, dialysis and anion exchange chromatography

recombinant iPGAM

recombinant iPGM

recombinant phosphoglycerate mutase

recombinant protein

recombinant protein expressed in Escherichia coli

Pyrococcus horikoshii

677357