5.4.2.12: phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

This is an abbreviated version!
For detailed information about phosphoglycerate mutase (2,3-diphosphoglycerate-independent), go to the full flat file.

Reaction

Synonyms

2,3-biphosphoglycerate-independent phosphoglycerate mutase, 2,3-diphosphoglycerate-independent phosphoglycerate mutase, 2,3BPG-independent PGAM, 3-phosphoglycerate mutase, apgM, co-factor-independent phosphoglycerate mutase, cofactor independent phosphoglycerate mutase, cofactor-independent phosphoglycerate mutase, cofactor-independent phosphoglycerate mutase 1, EC 2.7.5.3, EC 5.4.2.1, independent PGAM, independent PGM, iPGAM, iPGM, MJ0010, MJ1612, PGAM, PGM, PH0037, SSO0417

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.2 Phosphotransferases (phosphomutases)

                5.4.2.12 phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

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Results	in table
23	Activating Compound
32490	AA Sequence
3	Application
32	Cloned(Commentary)
31	Cofactor
11	Crystallization (Commentary)
5	General Information
2	General Stability
5	IC50 Value
84	Inhibitors
9	kcat/KM [mM/s]
51	KM Value [mM]
11	Localization
29	Metals/Ions
37	Molecular Weight [Da]
41	Natural Substrates/ Products (Substrates)
132	Organism
26	Pathway
19	PDB ID
25	pH Optimum
13	pH Range
5	pH Stability
5	pI Value
1	Posttranslational Modification
18	Protein Variants
42	Purification (Commentary)
2	Reaction
86	Reference
6	Renatured (Commentary)
18	Source Tissue
31	Specific Activity [micromol/min/mg]
6	Storage Stability
78	Substrates and Products (Substrate)
32	Subunits
66	Synonyms
1	Systematic Name
3	Temperature Optimum [°C]
5	Temperature Stability [°C]
19	Turnover Number [1/s]

Substrates Products

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Substrates Products on EC 5.4.2.12 - phosphoglycerate mutase (2,3-diphosphoglycerate-independent)

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2-phospho-D-glycerate

3-phospho-D-glycerate

46 entries

2-Phosphoglycerate

3-Phosphoglycerate

2 entries

2-[5-amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide

?

Geobacillus stearothermophilus

Q9X519

-

653052

-

-

?

3-phospho-D-glycerate

2-phospho-D-glycerate

24 entries

3-Phosphoglycerate

2-Phosphoglycerate

5 entries

2-phospho-D-glycerate

3-phospho-D-glycerate

Arabidopsis thaliana

O04499, Q9M9K1

-

728053

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Archaeoglobus fulgidus

-

-

679715

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Bacillus anthracis

Q81X77

-

678734

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Bacillus subtilis

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Brugia malayi

-

-

747238

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Brugia malayi

Q4VWF8

-

662259, 749047

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Brugia malayi

-

-

749047

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Caenorhabditis elegans

G5EFZ1

-

662259, 749047

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Caenorhabditis elegans

-

-

749047

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Clostridium perfringens

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Dirofilaria immitis

F4ZE01

-

716984

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Entamoeba histolytica

-

-

661689

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Entamoeba histolytica

C4LTW4

-

748541

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Entamoeba histolytica HM1 IMSS

C4LTW4

-

748541

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Geobacillus stearothermophilus

-

-

652915

-

652915

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Geobacillus stearothermophilus

Q9X519

-

650970

-

650970

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Geobacillus stearothermophilus

Q9X519

-

653052

-

653052

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Leishmania donovani

-

-

748833

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Leishmania donovani

D7R810

-

748834

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Leishmania mexicana

Q86N96

-

649202

-

649202

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Leishmania mexicana

Q86N96

-

661634, 705169

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Leishmania mexicana

-

-

705169

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Methanocaldococcus jannaschii

-

-

651372

-

651372

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Methanocaldococcus jannaschii

Q59007, Q60326

-

727503

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Methanocaldococcus jannaschii DSM 2661

Q59007, Q60326

-

727503

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Micrococcus luteus

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Planococcus citreus

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Pyrococcus furiosus

-

-

651372

-

651372

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Ricinus communis

-

-

3243

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Saccharolobus solfataricus

Q980A0

-

734842

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Saccharolobus solfataricus

Q980A0

-

651716

-

651716

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Saccharolobus solfataricus DSM 1617

Q980A0

-

734842

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Sporosarcina ureae

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Staphylococcus aureus

Q2G029

-

746646

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Staphylococcus aureus

Q2G029

-

747737

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Staphylococcus aureus NCTC 8325

Q2G029

-

746646

-

-

?

2-phospho-D-glycerate

3-phospho-D-glycerate

Staphylococcus aureus NCTC 8325

Q2G029

-

747737

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Staphylococcus saprophyticus

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Streptomyces coelicolor

-

-

650753

-

650753

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Thermoplasma acidophilum

Q9HL27

-

679715

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Trypanosoma brucei

Q9NG18

-

651058

-

651058

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Trypanosoma brucei

Q9NG18

-

727472

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Ustilago maydis

-

-

692403

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Wolbachia endosymbiont of Dirofilaria immitis

F4ZE02

-

716984

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Wolbachia sp.

-

-

716984

-

-

r

2-phospho-D-glycerate

3-phospho-D-glycerate

Wolbachia sp.

Q5GSN3

-

694538

-

-

r

2-Phosphoglycerate

3-Phosphoglycerate

Bacillus subtilis

-

-

3250

-

-

?

2-Phosphoglycerate

3-Phosphoglycerate

Pseudomonas syringae

-

-

3225

-

-

?

3-phospho-D-glycerate

2-phospho-D-glycerate

Archaeoglobus fulgidus

-

-

679715

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Bacillus anthracis

Q81X77

-

678734

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Brugia malayi

-

-

747238

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Brugia malayi

Q4VWF8

-

662259, 749047

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Brugia malayi

-

-

749047

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Caenorhabditis elegans

G5EFZ1

-

662259, 749047

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Caenorhabditis elegans

-

-

749047

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Dirofilaria immitis

F4ZE01

-

716984

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Entamoeba histolytica

-

-

661689

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Entamoeba histolytica

C4LTW4

-

748541

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Entamoeba histolytica HM1 IMSS

C4LTW4

-

748541

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Leishmania donovani

-

-

748833

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Leishmania donovani

D7R810

-

748834

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Leishmania mexicana

Q86N96

-

661634

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Methanocaldococcus jannaschii

-

-

651372

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Ricinus communis

-

-

3243

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Saccharolobus solfataricus

Q980A0

-

734842

-

-

?

3-phospho-D-glycerate

2-phospho-D-glycerate

Saccharolobus solfataricus DSM 1617

Q980A0

-

734842

-

-

?

3-phospho-D-glycerate

2-phospho-D-glycerate

Staphylococcus aureus

Q2G029

-

747737

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Staphylococcus aureus NCTC 8325

Q2G029

-

747737

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Thermoplasma acidophilum

Q9HL27

-

679715

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Trypanosoma brucei

Q9NG18

-

727472

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Wolbachia endosymbiont of Dirofilaria immitis

F4ZE02

-

716984

-

-

r

3-phospho-D-glycerate

2-phospho-D-glycerate

Wolbachia sp.

-

-

716984

-

-

r

3-Phosphoglycerate

2-Phosphoglycerate

Bacillus subtilis

-

-

3250

-

-

?

3-Phosphoglycerate

2-Phosphoglycerate

Oryza sativa

-

-

3259

-

-

?

3-Phosphoglycerate

2-Phosphoglycerate

Triticum aestivum

-

r

3259

-

-

?

3-Phosphoglycerate

2-Phosphoglycerate

Zea mays

-

r

3234

-

3234

?

3-Phosphoglycerate

2-Phosphoglycerate

Zymomonas mobilis

-

-

3241

-

-

?