5.3.3.2: isopentenyl-diphosphate DELTA-isomerase

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For detailed information about isopentenyl-diphosphate DELTA-isomerase, go to the full flat file.

Reaction

Synonyms

fcd1, FNI, IDI, IDI-1, Idi-2, IDI1, IDP isomerase, IPI, IPI1, IPP isomerase, IPP-isomerase, IPP:DMAPP, IPPI, IPPI1, IPPI2, IPPISOM, Isomerase, isopentenylpyrophosphate DELTA-, Isopententenyl diphosphate:dimethylallyl diphosphate isomerase, isopentenyl diphosphate isomerase, isopentenyl diphosphate isomerase 1, isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Isopentenyl pyrophosphate isomerase:dimethylallyl pyrophosphate isomerase, isopentenyl-diphosphate delta-isomerase 1, Isopentenyldiphosphate DELTA-isomerase, Isopentenylpyrophosphate isomerase, Methylbutenylpyrophosphate isomerase, SlIPI, type 1 IPP isomerase, type 2 isopentenyl diphosphate isomerase, type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase, type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type 2 isopentenyl-diphosphate isomerase, type I isopentenyl diphosphate isomerase, type II isopentenyl diphosphate isomerase, type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type-2 isopentenyl diphosphate isomerase, type-I isopentenyl pyrophosphate isomerase

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.3 Transposing C=C bonds

                5.3.3.2 isopentenyl-diphosphate DELTA-isomerase

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Results	in table
10	Activating Compound
23028	AA Sequence
9	Application
1	CAS Registry Number
44	Cloned(Commentary)
31	Cofactor
20	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
7	General Information
2	General Stability
13	IC50 Value
127	Inhibitors
8	kcat/KM [mM/s]
17	Ki Value [mM]
76	KM Value [mM]
21	Localization
83	Metals/Ions
35	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
125	Organism
15	Pathway
96	PDB ID
16	pH Optimum
3	pH Range
9	pI Value
63	Protein Variants
36	Purification (Commentary)
6	Reaction
8	Reaction Type
117	Reference
3	Renatured (Commentary)
66	Source Tissue
36	Specific Activity [micromol/min/mg]
3	Storage Stability
114	Substrates and Products (Substrate)
33	Subunits
90	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
23	Turnover Number [1/s]

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RENATURED/Commentary

ORGANISM

UNIPROT

LITERATURE

enzyme purified under aerobic conditions is inactive until the flavin cofactor is reduced by NADPH or dithionite or photochemically

Thermus thermophilus

-

678278

reconstitution of apo-enzyme with 5-deaza-FMN results in an inactive enzyme, whereas reconstitution with 1-deaza-FMN leads to full recovery of activity

Staphylococcus aureus

-

678309

reconstitution of metal-free enzyme with Mg2+, Mn2+, Zn2+, Co2+, Ni2+ or Cd2+ generates active enzyme

Escherichia coli

-

680346