5.3.3.2: isopentenyl-diphosphate DELTA-isomerase

This is an abbreviated version!
For detailed information about isopentenyl-diphosphate DELTA-isomerase, go to the full flat file.

Reaction

Synonyms

fcd1, FNI, IDI, IDI-1, Idi-2, IDI1, IDP isomerase, IPI, IPI1, IPP isomerase, IPP-isomerase, IPP:DMAPP, IPPI, IPPI1, IPPI2, IPPISOM, Isomerase, isopentenylpyrophosphate DELTA-, Isopententenyl diphosphate:dimethylallyl diphosphate isomerase, isopentenyl diphosphate isomerase, isopentenyl diphosphate isomerase 1, isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Isopentenyl pyrophosphate isomerase:dimethylallyl pyrophosphate isomerase, isopentenyl-diphosphate delta-isomerase 1, Isopentenyldiphosphate DELTA-isomerase, Isopentenylpyrophosphate isomerase, Methylbutenylpyrophosphate isomerase, SlIPI, type 1 IPP isomerase, type 2 isopentenyl diphosphate isomerase, type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase, type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type 2 isopentenyl-diphosphate isomerase, type I isopentenyl diphosphate isomerase, type II isopentenyl diphosphate isomerase, type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type-2 isopentenyl diphosphate isomerase, type-I isopentenyl pyrophosphate isomerase

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.3 Transposing C=C bonds

                5.3.3.2 isopentenyl-diphosphate DELTA-isomerase

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Results	in table
10	Activating Compound
23028	AA Sequence
9	Application
1	CAS Registry Number
44	Cloned(Commentary)
31	Cofactor
20	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
7	General Information
2	General Stability
13	IC50 Value
127	Inhibitors
8	kcat/KM [mM/s]
17	Ki Value [mM]
76	KM Value [mM]
21	Localization
83	Metals/Ions
35	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
125	Organism
15	Pathway
96	PDB ID
16	pH Optimum
3	pH Range
9	pI Value
63	Protein Variants
36	Purification (Commentary)
6	Reaction
8	Reaction Type
117	Reference
3	Renatured (Commentary)
66	Source Tissue
36	Specific Activity [micromol/min/mg]
3	Storage Stability
114	Substrates and Products (Substrate)
33	Subunits
90	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
23	Turnover Number [1/s]

KI Value

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KI Value on EC 5.3.3.2 - isopentenyl-diphosphate DELTA-isomerase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

0.383

(Z)-3-difluoromethyl-2-buten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.012

(Z)-3-fluoromethyl-2-buten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.031 - 0.036

2,3-butadien-1-yl diphosphate

2 entries

0.0565

3,4-epoxy-3-methylbutyl diphosphate

Methanocaldococcus jannaschii

-

pH 7.0, 85°C

678586

0.0486

3,4-oxido-3-methyl-1-butyl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.0074

3-(Fluoromethyl)-3-buten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.048 - 0.049

3-butyn-1-yl diphosphate

2 entries

0.054

3-cyclopropyl-3-buten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.008

3-methylene-4-penten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

692765

0.0014

3-oxiranyl-3-buten-1-yl diphosphate

Thermus thermophilus

-

pH 7.0, 37°C

693801

0.00013

5-deaza-FMN

Saccharolobus shibatae

-

-

660882

0.0064

FMN

2 entries

0.292

isopentenyl diphosphate

2 entries

0.031

2,3-butadien-1-yl diphosphate

Escherichia coli

-

in 50 mM HEPES (pH 7.2) containing 10 mM MgCl2, 200 mM KCl, 1 mg/ml bovine serum albumin, 0.5 mM dithiothreitol, at 37°C

714202

0.036

2,3-butadien-1-yl diphosphate

Thermus thermophilus

-

in 200 mM HEPES (pH 7.0) containing 2 mM MgCl2, 0.04 mM FMN, 2 mM NADPH, at 37°C

714202

0.048

3-butyn-1-yl diphosphate

Thermus thermophilus

-

in 200 mM HEPES (pH 7.0) containing 2 mM MgCl2, 0.04 mM FMN, 2 mM NADPH, at 37°C

714202

0.049

3-butyn-1-yl diphosphate

Escherichia coli

-

in 50 mM HEPES (pH 7.2) containing 10 mM MgCl2, 200 mM KCl, 1 mg/ml bovine serum albumin, 0.5 mM dithiothreitol, at 37°C

714202

0.0064

FMN

Streptococcus pneumoniae

B2ILS5

at pH 7.0 and 37°C

747530

0.0064

FMN

Streptococcus pneumoniae

-

wild type enzyme, at anaerobic conditions, at pH 7.0 and 37°C

747106

0.292

isopentenyl diphosphate

Streptococcus pneumoniae

B2ILS5

at pH 7.0 and 37°C

747530

0.292

isopentenyl diphosphate

Streptococcus pneumoniae

-

wild type enzyme, at aerobic conditions, at pH 7.0 and 37°C

747106