5.3.3.2: isopentenyl-diphosphate DELTA-isomerase

This is an abbreviated version!
For detailed information about isopentenyl-diphosphate DELTA-isomerase, go to the full flat file.

Reaction

Synonyms

fcd1, FNI, IDI, IDI-1, Idi-2, IDI1, IDP isomerase, IPI, IPI1, IPP isomerase, IPP-isomerase, IPP:DMAPP, IPPI, IPPI1, IPPI2, IPPISOM, Isomerase, isopentenylpyrophosphate DELTA-, Isopententenyl diphosphate:dimethylallyl diphosphate isomerase, isopentenyl diphosphate isomerase, isopentenyl diphosphate isomerase 1, isopentenyl diphosphate:dimethylallyl diphosphate isomerase, Isopentenyl pyrophosphate isomerase, Isopentenyl pyrophosphate isomerase:dimethylallyl pyrophosphate isomerase, isopentenyl-diphosphate delta-isomerase 1, Isopentenyldiphosphate DELTA-isomerase, Isopentenylpyrophosphate isomerase, Methylbutenylpyrophosphate isomerase, SlIPI, type 1 IPP isomerase, type 2 isopentenyl diphosphate isomerase, type 2 isopentenyl diphosphate: dimethylallyl diphosphate isomerase, type 2 isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type 2 isopentenyl-diphosphate isomerase, type I isopentenyl diphosphate isomerase, type II isopentenyl diphosphate isomerase, type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase, type-2 isopentenyl diphosphate isomerase, type-I isopentenyl pyrophosphate isomerase

ECTree

     5 Isomerases

         5.3 Intramolecular oxidoreductases

             5.3.3 Transposing C=C bonds

                5.3.3.2 isopentenyl-diphosphate DELTA-isomerase

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Results	in table
10	Activating Compound
23028	AA Sequence
9	Application
1	CAS Registry Number
44	Cloned(Commentary)
31	Cofactor
20	Crystallization (Commentary)
10	Disease/ Diagnostics
2	Expression
7	General Information
2	General Stability
13	IC50 Value
127	Inhibitors
8	kcat/KM [mM/s]
17	Ki Value [mM]
76	KM Value [mM]
21	Localization
83	Metals/Ions
35	Molecular Weight [Da]
40	Natural Substrates/ Products (Substrates)
125	Organism
15	Pathway
96	PDB ID
16	pH Optimum
3	pH Range
9	pI Value
63	Protein Variants
36	Purification (Commentary)
6	Reaction
8	Reaction Type
117	Reference
3	Renatured (Commentary)
66	Source Tissue
36	Specific Activity [micromol/min/mg]
3	Storage Stability
114	Substrates and Products (Substrate)
33	Subunits
90	Synonyms
1	Systematic Name
7	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]
23	Turnover Number [1/s]

Disease

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Disease on EC 5.3.3.2 - isopentenyl-diphosphate DELTA-isomerase

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DISEASE

TITLE OF PUBLICATION

LINK TO PUBMED

Amyotrophic Lateral Sclerosis

Segmental copy-number gain within the region of isopentenyl diphosphate isomerase genes in sporadic amyotrophic lateral sclerosis.

20955688

Bacterial Infections

Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus.

17585782

isopentenyl-diphosphate delta-isomerase deficiency

Isopentenyl diphosphate isomerase deficiency in Synechocystis sp. strain PCC6803.

10818236

Neoplasms

Proliferation of NS0 cells in protein-free medium: the role of cell-derived proteins, known growth factors and cellular receptors.

19433215

Paralysis

Isopentenyl-diphosphate isomerase is essential for viability of Caenorhabditis elegans.

15765206

Zellweger Syndrome

Cholesterol biosynthesis in Zellweger syndrome: normal activity of mevalonate kinase, mevalonate-5'-pyrophosphate decarboxylase and IPP-isomerase in patients' fibroblasts but deficient mevalonate kinase activity in liver.

8739963

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