4.6.1.17: cyclic pyranopterin monophosphate synthase
This is an abbreviated version!
For detailed information about cyclic pyranopterin monophosphate synthase, go to the full flat file.
Reaction
Synonyms
cnx3, cyclic pyranopterin monophosphate synthase accessory protein, EC 4.1.99.18, MoaC, MoaC2, Moco-biosynthesis protein, MOCS1B, molybdenum cofactor biosynthesis protein C, ST0472
ECTree
Advanced search results
Inhibitors
Inhibitors on EC 4.6.1.17 - cyclic pyranopterin monophosphate synthase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-P-CH2-PP
-
compound is converted to an analogue of the MoaC reaction intermediate and causes mechanism-based inhibition. the reaction product harbors an acid-labile triaminopyrimidinone base without an established pyranopterin structure and forms a tight complex with MoaC likely through a covalent linkage