4.6.1.17: cyclic pyranopterin monophosphate synthase
This is an abbreviated version!
For detailed information about cyclic pyranopterin monophosphate synthase, go to the full flat file.
Reaction
Synonyms
cnx3, cyclic pyranopterin monophosphate synthase accessory protein, EC 4.1.99.18, MoaC, MoaC2, Moco-biosynthesis protein, MOCS1B, molybdenum cofactor biosynthesis protein C, ST0472
ECTree
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Systematic Name
Systematic Name on EC 4.6.1.17 - cyclic pyranopterin monophosphate synthase
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(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate lyase (cyclic pyranopterin phosphate-forming)
The enzyme catalyses an early step in the biosynthesis of the molybdenum cofactor (MoCo). In bacteria and plants the reaction is catalysed by MoaC and Cnx3, respectively. In mammals the reaction is catalysed by the MOCS1B domain of the bifuctional MOCS1 protein, which also catalyses EC 4.1.99.22, GTP 3',8-cyclase.