4.5.1.B1: hexachlorocyclohexane dehydrochlorinase

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For detailed information about hexachlorocyclohexane dehydrochlorinase, go to the full flat file.

Reaction

Synonyms

dehydrochlorinase, gamma-HCH dehydrochlorinase, gamma-hexachlorocyclohexane dehydrochlorinase, HCH dehydrochlorinase, LinA, LinA-type1, LinA-type2, LinA-UT26, Lina1, Lina2

ECTree

     4 Lyases

         4.5 Carbon-halide lyases

             4.5.1 Carbon-halide lyases (only sub-subclass identified to date)

                4.5.1.B1 hexachlorocyclohexane dehydrochlorinase

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Results	in table
15	AA Sequence
6	Cloned(Commentary)
2	Crystallization (Commentary)
7	General Information
9	Localization
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
43	Organism
2	pH Optimum
2	Purification (Commentary)
2	Reaction
28	Reference
66	Substrates and Products (Substrate)
12	Subunits
62	Synonyms
3	Temperature Optimum [°C]
2	Temperature Range [°C]
6	Temperature Stability [°C]

Crystallization

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Crystallization on EC 4.5.1.B1 - hexachlorocyclohexane dehydrochlorinase

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CRYSTALLIZATION (Commentary)

ORGANISM

UNIPROT

LITERATURE

quantum mechanics/molecular mechanics study. In the degradation process, two discontinuous dehydrochlorination reactions with the Boltzmann-weighted average potential barriers of 16.2 and 17.3 kcal/mol are connected by a conformational transition with a barrier of 11.1 kcal /mol. Residue Phe68 facilitates the dehydrochlorination of gamma-hexachlorohexane, whereas Leu21 and Cys71 suppress it

Sphingobium indicum

P51697

749288

using 100 mM HEPES-Na (pH 7.0), 16% (w/v) polyethylene glycol 3350, and 200 mM ammonium acetate

Sphingobium indicum

-

715918