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4.4.1.23: 2-hydroxypropyl-CoM lyase

This is an abbreviated version!
For detailed information about 2-hydroxypropyl-CoM lyase, go to the full flat file.

Word Map on EC 4.4.1.23

Reaction

(R)-2-Hydroxypropyl-CoM
=
(R)-1,2-epoxypropane
+
HS-CoM

Synonyms

coenzyme M-epoxyalkane ligase, Ea-CoMT, EaCoMT, EC 4.2.99.19, epoxyalkane coenzyme M transferase, epoxyalkane:2-mercaptoethanesulfonate transferase, epoxyalkane:CoM transferase, epoxyalkyl:CoM transferase, epoxypropane:coenzyme M transferase, epoxypropyl:CoM transferase, EtnE, transferase, epoxyalkyl:coenzyme M

ECTree

     4 Lyases
         4.4 Carbon-sulfur lyases
             4.4.1 Carbon-sulfur lyases (only sub-subclass identified to date)
                4.4.1.23 2-hydroxypropyl-CoM lyase

Substrates Products

Substrates Products on EC 4.4.1.23 - 2-hydroxypropyl-CoM lyase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-hydroxypropyl-CoM
1,2-epoxypropane + HS-CoM
show the reaction diagram
epoxyethane + CoM
2-hydroxyethyl-CoM
show the reaction diagram
assay at pH 8.0, 30°C
-
-
?
epoxyethane + HS-CoM
2-hydroxyethyl-CoM
show the reaction diagram
epoxypropane + 3-mercaptopropionate
3-[(2-hydroxypropyl)thio]propanoic acid
show the reaction diagram
-
0.59% of the activity with HS-CoM
-
-
?
epoxypropane + HS-CoA
?
show the reaction diagram
epoxypropane + HS-CoM
2-hydroxypropyl-CoM
show the reaction diagram
ethene + HS-CoM
?
show the reaction diagram
ethylene oxide + HS-CoM
?
show the reaction diagram
vinyl chloride + HS-CoM
?
show the reaction diagram