4.3.1.25: phenylalanine/tyrosine ammonia-lyase
This is an abbreviated version!
For detailed information about phenylalanine/tyrosine ammonia-lyase, go to the full flat file.
Word Map on EC 4.3.1.25
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4.3.1.25
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synthesis
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deamination
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rhodotorula
-
glutinis
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p-hydroxycinnamic
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hydrolysate
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pharmacology
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analysis
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food industry
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medicine
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nutrition
- 4.3.1.25
- synthesis
-
deamination
-
rhodotorula
- glutinis
-
p-hydroxycinnamic
- hydrolysate
- pharmacology
- analysis
- food industry
- medicine
- nutrition
Reaction
Synonyms
EC 4.3.1.5, PAL, PAL/TAL, PAL4, phenylalanine-tyrosine ammonia lyase, PTAL, RtPAL, Sb04g026510, Sb06g022740, SbPAL1
ECTree
4.3.1.25 phenylalanine/tyrosine ammonia-lyaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 4.3.1.25 - phenylalanine/tyrosine ammonia-lyase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
2-chloro-trans-cinnamate + NH3
2-chloro-L-phenylalanine
51.4% conversion
-
-
?
2-fluoro-trans-cinnamate + NH3
2-fluoro-L-phenylalanine
94.3% conversion
-
-
?
2-hydroxy-trans-cinnamate + NH3
2-hydroxy-L-phenylalanine
15.7% conversion
-
-
?
2-methoxy-trans-cinnamate + NH3
2-methoxy-L-phenylalanine
64.9% conversion
-
-
?
3-chloro-trans-cinnamate + NH3
3-chloro-L-phenylalanine
71.6% conversion
-
-
?
3-fluoro-trans-cinnamate + NH3
3-fluoro-L-phenylalanine
61.5% conversion
-
-
?
3-hydroxy-trans-cinnamate + NH3
3-hydroxy-L-phenylalanine
30.3% conversion
-
-
?
3-methoxy-4-hydroxy-trans-cinnamate + NH3
3-methoxy-4-hydroxy-L-phenylalanine
60.3% conversion
-
-
?
3-methoxy-trans-cinnamate + NH3
3-methoxy-L-phenylalanine
77.8% conversion
-
-
?
4-fluoro-trans-cinnamate + NH3
4-fluoro-L-phenylalanine
57.5% conversion
-
-
?
4-hydroxy-trans-cinnamate + NH3
4-hydroxy-L-phenylalanine
61.1% conversion
-
-
?
4-methoxy-trans-cinnamate + NH3
4-methoxy-L-phenylalanine
0.7% conversion
-
-
?
L-tyrosine methyl ester
4-hydroxycinnamic acid methyl ester + NH3
-
-
-
-
?
L-phenylalanine
trans-cinnamate + NH3
key gateway enzyme linking the phenylpropanoid secondary pathway to primary metabolism
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-
r
L-phenylalanine
trans-cinnamate + NH3
the bifunctional enzyme shows KM-values for L-Phe and L-Tyr in the same order of magnitude
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-
r
L-phenylalanine
trans-cinnamate + NH3
enzyme of the phenylpropanoid pathway
-
-
?
L-tyrosine
p-coumarate + NH3
-
substrate binding is cooperative, nH 2.6
-
-
?
L-tyrosine
trans-p-hydroxycinnamate + NH3
the bifunctional enzyme shows KM-values for L-Phe and L-Tyr in the same order of magnitude
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-
?
additional information
?
-
wild type enzyme and mutants show no catalytic activity with His
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-
?
additional information
?
-
wild type enzyme and mutants show no catalytic activity with His
-
-
?
