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4.3.1.25: phenylalanine/tyrosine ammonia-lyase

This is an abbreviated version!
For detailed information about phenylalanine/tyrosine ammonia-lyase, go to the full flat file.

Word Map on EC 4.3.1.25

Reaction

L-phenylalanine
=
trans-cinnamate
+
NH3

Synonyms

EC 4.3.1.5, PAL, PAL/TAL, PAL4, phenylalanine-tyrosine ammonia lyase, PTAL, RtPAL, Sb04g026510, Sb06g022740, SbPAL1

ECTree

     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.1 Ammonia-lyases
                4.3.1.25 phenylalanine/tyrosine ammonia-lyase

Inhibitors

Inhibitors on EC 4.3.1.25 - phenylalanine/tyrosine ammonia-lyase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-hydroxycinnamic acid
-
-
4-coumarate
5,5'-dithiobis(2-nitrobenzoate)
-
-
Acetic anhydride
Aminooxyacetate
-
-
benzyl alcohol
-
-
Br-
-
competitive
Cinnamic acid
Cl-
-
competitive
Co2+
-
strong
Cu2+
-
strong
D-Phe
dihydrocaffeic acid
-
-
DL-2-hydroxyphenylalanine
-
-
Fe3+
-
strong
fluorophenylalanine
-
-
glycine
-
3.54 mM, 50% inhibition
I-
-
competitive
L-beta-phenyllactic acid
-
-
L-phenylserine
-
-
m-cresol
-
9.9 mM, 50% inhibition
m-cresol/glycine
-
0.387 mM, 50% inhibition, strong synergistic inhibition
Ni2+
-
strong
o-Cresol
-
2.93 mM, 50% inhibition
o-cresol/glycine
-
0.078 mM, 50% inhibition, strong synergistic inhibition
p-chloromercuribenzoate
-
-
p-cresol/glycine
-
1.03 mM, 50% inhibition
p-hydroxymercuribenzoate
-
-
phenol
-
3.89 mM, 50% inhibition
phenol/glycine
-
0.056 mM 50% inhibition, strong synergistic inhibition
phenylpyruvate
trinitrobenzene sulfonic acid
Zn2+
-
weak
additional information
-
not inhibited by p-cresol
-