4.3.1.18: D-Serine ammonia-lyase

This is an abbreviated version!
For detailed information about D-Serine ammonia-lyase, go to the full flat file.

Reaction

Synonyms

chDSD, D-Hydroxy amino acid dehydratase, D-Ser dehydratase, D-serine ammonia lyase, D-serine ammonia-lyase, D-Serine deaminase, D-Serine dehydrase, D-serine dehydratase, D-Serine hydrolase (deaminating), DDB_G0289463, Dehydratase, D-serine, DSD, Dsd1p, DsdA, Dsdase, DsdSC, EC 4.2.1.14, PA3357, PH0054, Serine deaminase

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.1 Ammonia-lyases

                4.3.1.18 D-Serine ammonia-lyase

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Results	in table
1	Activating Compound
5310	AA Sequence
10	Application
1	CAS Registry Number
10	Cloned(Commentary)
26	Cofactor
10	Crystallization (Commentary)
1	Expression
7	General Information
2	General Stability
24	Inhibitors
8	kcat/KM [mM/s]
8	Ki Value [mM]
60	KM Value [mM]
1	Localization
9	Metals/Ions
14	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
56	Organism
5	Pathway
45	PDB ID
14	pH Optimum
3	pH Range
14	Protein Variants
16	Purification (Commentary)
4	Reaction
10	Reaction Type
51	Reference
1	Renatured (Commentary)
14	Source Tissue
15	Specific Activity [micromol/min/mg]
1	Storage Stability
72	Substrates and Products (Substrate)
8	Subunits
66	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
7	Temperature Stability [°C]
46	Turnover Number [1/s]

pH Range

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pH Range on EC 4.3.1.18 - D-Serine ammonia-lyase

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pH RANGE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

6 - 8.5

Klebsiella pneumoniae

-

pH 6.0: about 30% of maximal activity, pH 8.5: about 60% of maximal activity

210807

6.5 - 11.5

Gallus gallus

-

in the range of pH 6.5-11.5 the enzyme has an activity between 50 and 100% with an maximum at pH 9

680567

6.5 - 9

Escherichia coli

-

pH 6.5: about 30% of maximal activity, pH 9.0: about 60% of maximal activity

210811