4.3.1.18: D-Serine ammonia-lyase

This is an abbreviated version!
For detailed information about D-Serine ammonia-lyase, go to the full flat file.

Reaction

Synonyms

chDSD, D-Hydroxy amino acid dehydratase, D-Ser dehydratase, D-serine ammonia lyase, D-serine ammonia-lyase, D-Serine deaminase, D-Serine dehydrase, D-serine dehydratase, D-Serine hydrolase (deaminating), DDB_G0289463, Dehydratase, D-serine, DSD, Dsd1p, DsdA, Dsdase, DsdSC, EC 4.2.1.14, PA3357, PH0054, Serine deaminase

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.1 Ammonia-lyases

                4.3.1.18 D-Serine ammonia-lyase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
5310	AA Sequence
10	Application
1	CAS Registry Number
10	Cloned(Commentary)
26	Cofactor
10	Crystallization (Commentary)
1	Expression
7	General Information
2	General Stability
24	Inhibitors
8	kcat/KM [mM/s]
8	Ki Value [mM]
60	KM Value [mM]
1	Localization
9	Metals/Ions
14	Molecular Weight [Da]
18	Natural Substrates/ Products (Substrates)
56	Organism
5	Pathway
45	PDB ID
14	pH Optimum
3	pH Range
14	Protein Variants
16	Purification (Commentary)
4	Reaction
10	Reaction Type
51	Reference
1	Renatured (Commentary)
14	Source Tissue
15	Specific Activity [micromol/min/mg]
1	Storage Stability
72	Substrates and Products (Substrate)
8	Subunits
66	Synonyms
1	Systematic Name
14	Temperature Optimum [°C]
7	Temperature Stability [°C]
46	Turnover Number [1/s]

General Information

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

General Information on EC 4.3.1.18 - D-Serine ammonia-lyase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide show all columns Go to General Information Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

GENERAL INFORMATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

malfunction

3 entries

metabolism

3 entries

physiological function

Staphylococcus saprophyticus

Q4A041

DsdA contributes to virulence within the urinary tract of mice

729822

malfunction

Staphylococcus saprophyticus

Q4A041

a dsdA mutant is attenuated in virulence

729822

malfunction

Dictyostelium discoideum

Q54HH2

dsd-null cells exhibit delay in development and arrest at the early culmination stage. The efficiency of spore formation is considerably reduced in the mutant cells

747858

malfunction

Dictyostelium discoideum AX2

-

dsd-null cells exhibit delay in development and arrest at the early culmination stage. The efficiency of spore formation is considerably reduced in the mutant cells

-

metabolism

Pseudomonas aeruginosa

Q9HYN9

due to its low level of expression and the lack of induction by exogenous D-serine, this dsdA gene does not have any apparent contribution to D-serine utilization in Pseudomonas aeruginosa PAO1. However, a high level of DsdA when overexpressed from a recombinant plasmid is able to support growth on D-serine as the sole source of carbon and nitrogen

747622

metabolism

Dictyostelium discoideum

Q54HH2

the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser. D-Ser dehydrogenase is the primary enzyme responsible for D-Ser decomposition in Dictyostelium discoideum

747858

metabolism

Dictyostelium discoideum AX2

-

the enzyme is 460fold and 1700fold more active than D-amino acid oxidase and serine racemase, respectively, in degrading D-Ser. D-Ser dehydrogenase is the primary enzyme responsible for D-Ser decomposition in Dictyostelium discoideum

-