4.3.1.16: threo-3-hydroxy-L-aspartate ammonia-lyase

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For detailed information about threo-3-hydroxy-L-aspartate ammonia-lyase, go to the full flat file.

Reaction

Synonyms

D-THA DH, D-threo-3-hydroxyaspartate dehydratase, L-THA DH, L-threo-3-hydroxyaspartate dehydratase, threo-3-hydroxyaspartate ammonia-lyase, threo-3-hydroxyaspartate dehydratase

ECTree

     4 Lyases

         4.3 Carbon-nitrogen lyases

             4.3.1 Ammonia-lyases

                4.3.1.16 threo-3-hydroxy-L-aspartate ammonia-lyase

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Results	in table
2	Activating Compound
1107	AA Sequence
1	Application
1	CAS Registry Number
3	Cloned(Commentary)
2	Cofactor
1	Crystallization (Commentary)
13	Inhibitors
2	kcat/KM [mM/s]
3	Ki Value [mM]
5	KM Value [mM]
9	Metals/Ions
3	Molecular Weight [Da]
2	Natural Substrates/ Products (Substrates)
4	Organism
2	pH Optimum
1	Protein Variants
4	Purification (Commentary)
1	Reaction
2	Reaction Type
4	Reference
5	Specific Activity [micromol/min/mg]
6	Substrates and Products (Substrate)
2	Subunits
7	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]
2	Temperature Stability [°C]
2	Turnover Number [1/s]

KI Value

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KI Value on EC 4.3.1.16 - threo-3-hydroxy-L-aspartate ammonia-lyase

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Ki VALUE [mM]

INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

22.8

D-serine

Pseudomonas sp. T62

A4F2N8

non-competitive inhibition

692924

0.2

L-erythro-3-hydroxyaspartate

Pseudomonas sp. T62

A4F2N8

strong competitive inhibition

692924

additional information

additional information

Pseudomonas sp. T62

A4F2N8

DL-aspartate, L-serine, DL-threonine, DL-allo-threonine, DL-phenylserine, or malonic acid did not cause significant inhibition of the enzyme reaction at 5 mM

692924

-