4.2.3.82: alpha-santalene synthase

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For detailed information about alpha-santalene synthase, go to the full flat file.

Word Map on EC 4.2.3.82

4.2.3.82

terpene

sandalwood

sesquiterpene

santalols

synthases

santalum

album

mevalonate

clausena

lansium

pyrophosphate

fed-batch

cyclization

sesquiterpenoids

monoterpene

heartwood

unigenes

sassy

bergamotene

synthesis

Reaction

Synonyms

SanSyn, santalene synthase, SaSSy, SspiSy, SSy, SuSSy, Tps2-1

ECTree

4 Lyases

4.2 Carbon-oxygen lyases

4.2.3 Acting on phosphates

4.2.3.82 alpha-santalene synthase

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Results	in table
5	AA Sequence
1	Application
10	Cloned(Commentary)
2	General Information
6	kcat/KM [mM/s]
12	KM Value [mM]
14	Metals/Ions
6	Molecular Weight [Da]
15	Natural Substrates/ Products (Substrates)
8	Organism
1	Pathway
4	PDB ID
6	pH Optimum
1	pI Value
3	Purification (Commentary)
1	Reaction
8	Reference
6	Source Tissue
2	Specific Activity [micromol/min/mg]
25	Substrates and Products (Substrate)
6	Subunits
13	Synonyms
1	Systematic Name
6	Temperature Optimum [°C]
9	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.3.82 - alpha-santalene synthase

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(2E,6E)-farnesyl diphosphate lyase (cyclizing, (+)-alpha-santalene-forming)

The enzyme synthesizes a mixture of sesquiterpenoids from (2E,6E)-farnesyl diphosphate. As well as (+)-alpha-santalene, (-)-beta-santalene and (-)-exo-alpha-bergamotene are formed with traces of (+)-epi-beta-santalene. See EC 4.2.3.83 [(-)-beta-santalene synthase], and EC 4.2.3.81 [(-)-exo-alpha-bergamotene synthase]. cf. EC 4.2.3.50 alpha-santalene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing]