4.2.1.126: N-acetylmuramic acid 6-phosphate etherase
This is an abbreviated version!
For detailed information about N-acetylmuramic acid 6-phosphate etherase, go to the full flat file.
Word Map on EC 4.2.1.126
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4.2.1.126
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peptidoglycan
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glcnac
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lactyl
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mayer
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n-acetylglucosamine-phosphate
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plasmalogens
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murein
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triethylene
- 4.2.1.126
- peptidoglycan
- glcnac
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lactyl
-
mayer
- n-acetylglucosamine-phosphate
- plasmalogens
- murein
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triethylene
Reaction
Synonyms
etherase, MurNAc 6-phosphate etherase, MurNAc 6-phosphate etherase lyase, MurNAc 6-phosphate hydrolase, MurNAc etherase, MurNAc-6-P etherase, MurNAc-6-phosphate etherase, MurQ, MurQ etherase, MurQ hydrolase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase, N-acetylmuramic acid-phosphate etherase, Tanf_08385, TfMurQ, YbbI
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Substrates Products
Substrates Products on EC 4.2.1.126 - N-acetylmuramic acid 6-phosphate etherase
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REACTION DIAGRAM
3-chloro-3-deoxy-N-acetylglucosamine 6-phosphate
(2E)-2-(acetylamino)-2,3-dideoxy-6-O-phosphono-D-erythro-hex-2-enose + HCl
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slow conversion, 2% activity compared to N-acetylmuramate 6-phosphate
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-
?
N-acetylmuramate 6-phosphate + H2O
D-lactate + N-acetyl-D-glucosamine 6-phosphate
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?
N-acetylmuramate 6-phosphate + H2O
N-acetyl-D-glucosamine 6-phosphate + D-lactate
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?
N-acetylmuramate 6-phosphate + H2O
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r
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
N-acetylmuramate 6-phosphate + H2O
Tannerella forsythia ATCC 43037 / JCM 10827 / FDC 338
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-
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r
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
the MurQ hydrolase catalyzes the cleavage of a nonlabile ether bond at the C3 position of N-acetylmuramate 6-phosphate
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-
?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
the MurQ hydrolase catalyzes the cleavage of a nonlabile ether bond at the C3 position of N-acetylmuramate 6-phosphate
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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?
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
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-
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r
N-acetylmuramate 6-phosphate + H2O
(R)-lactate + N-acetyl-D-glucosamine 6-phosphate
Tannerella forsythia ATCC 43037 / JCM 10827 / FDC 338
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r
?
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N-acetylmuramate is not a substrate nor are anhydro-N-acetylmuramate or muramic acid
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?
additional information
?
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the etherase activity is assessed by utilizing N-acetylmuramate 6-phosphate as the substrate in a Morgan Elson reaction. This etherase-catalyzed reaction generates a chromogenic intermediate that can be detected by reacting with Ehrlich's reagent dimethylaminobenzaldehyde to yield a purple product. Also, radioactive assay with 32P-radiolabeled substrates N-acetyl-D-glucosamine 6-phosphate and N-acetylmuramate 6-phosphate
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-
?
additional information
?
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the etherase activity is assessed by utilizing N-acetylmuramate 6-phosphate as the substrate in a Morgan Elson reaction. This etherase-catalyzed reaction generates a chromogenic intermediate that can be detected by reacting with Ehrlich's reagent dimethylaminobenzaldehyde to yield a purple product. Also, radioactive assay with 32P-radiolabeled substrates N-acetyl-D-glucosamine 6-phosphate and N-acetylmuramate 6-phosphate
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-
?
additional information
?
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Tannerella forsythia ATCC 43037 / JCM 10827 / FDC 338
the etherase activity is assessed by utilizing N-acetylmuramate 6-phosphate as the substrate in a Morgan Elson reaction. This etherase-catalyzed reaction generates a chromogenic intermediate that can be detected by reacting with Ehrlich's reagent dimethylaminobenzaldehyde to yield a purple product. Also, radioactive assay with 32P-radiolabeled substrates N-acetyl-D-glucosamine 6-phosphate and N-acetylmuramate 6-phosphate
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-
?