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4.2.1.126: N-acetylmuramic acid 6-phosphate etherase

This is an abbreviated version!
For detailed information about N-acetylmuramic acid 6-phosphate etherase, go to the full flat file.

Word Map on EC 4.2.1.126

Reaction

(R)-lactate
+
N-acetyl-D-glucosamine 6-phosphate
=
N-acetylmuramate 6-phosphate
+
H2O

Synonyms

etherase, MurNAc 6-phosphate etherase, MurNAc 6-phosphate etherase lyase, MurNAc 6-phosphate hydrolase, MurNAc etherase, MurNAc-6-P etherase, MurNAc-6-phosphate etherase, MurQ, MurQ etherase, MurQ hydrolase, N-acetylmuramic acid 6-phosphate hydrolase, N-acetylmuramic acid 6-phosphate lyase, N-acetylmuramic acid-phosphate etherase, Tanf_08385, TfMurQ, YbbI

ECTree

     4 Lyases
         4.2 Carbon-oxygen lyases
             4.2.1 Hydro-lyases
                4.2.1.126 N-acetylmuramic acid 6-phosphate etherase

Inhibitors

Inhibitors on EC 4.2.1.126 - N-acetylmuramic acid 6-phosphate etherase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(2R)-2-[[(2R,3R,4R)-5-(acetylamino)-2,3,7-trihydroxy-1-(phosphonooxy)heptan-4-yl]oxy]propanoic acid
a N-acetylmuramate 6-phosphate open chain analogue, competitive inhibition
(2R,3S,4R)-5-(acetylamino)-2,3,4,7-tetrahydroxyheptyl phosphate
a N-acetyl-D-glucosamine 6-phosphate open chain analogue, competitive inhibition
EDTA
-
5 mM EDTA results in only weak inhibition (25% reduction in rate)