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4.1.99.2: tyrosine phenol-lyase

This is an abbreviated version!
For detailed information about tyrosine phenol-lyase, go to the full flat file.

Word Map on EC 4.1.99.2

Reaction

L-tyrosine
+
H2O
=
phenol
+
pyruvate
+
NH3

Synonyms

beta-tyrosinase, Fn-TPL, L-tyrosine phenol-lyase, phenol-lyase, tyrosine, TnaA, TPL, tyrosine phenol lyase, tyrosine phenol-lyase, tyrosine-phenol lyase

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.99 Other carbon-carbon lyases
                4.1.99.2 tyrosine phenol-lyase

KCat KM Value

KCat KM Value on EC 4.1.99.2 - tyrosine phenol-lyase

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0092 - 14
3-fluoro-L-tyrosine
0.19 - 2.84
beta-chloro-L-alanine
0.09
L-Dopa
recombinant enzyme, pH 8.5, 20°C
0.0000008 - 17.5
L-tyrosine
0.12
phenol
recombinant enzyme, L-tyrosine formation is measured from phenol, pyruvate, and ammonium, pH 8.5, 20°C
0.0062 - 46
S-(2-nitrophenyl)-L-cysteine
0.0037 - 5.26
S-Benzyl-L-cysteine
0.000088 - 3.43
S-ethyl-L-cysteine
0.0042 - 0.49
S-methyl-L-cysteine