4.1.2.45: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

This is an abbreviated version!
For detailed information about trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, go to the full flat file.

Word Map on EC 4.1.2.45

4.1.2.45

naphthalene

salicylaldehyde

salicylate

dioxygenase

naphthalenesulfonates

fluorescens

putida

benzaldehyde

sphingomonas

1,2-dihydroxynaphthalene

Reaction

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate

Synonyms

2'-hydroxybenzalpyruvate aldolase, fHBP HA A, fHBP HA B, nsaE, o-tHBPA hydratase-aldolase, tHBP-HA, tHBPA hydratase-aldolase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.2 Aldehyde-lyases

4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

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Results	in table
20	AA Sequence
3	Cloned(Commentary)
1	Cofactor
1	General Stability
10	Inhibitors
1	Ki Value [mM]
8	KM Value [mM]
8	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
28	Organism
5	Pathway
2	PDB ID
3	pH Optimum
4	pH Range
3	pH Stability
3	pI Value
4	Purification (Commentary)
1	Reaction
2	Reaction Type
18	Reference
4	Specific Activity [micromol/min/mg]
76	Substrates and Products (Substrate)
9	Subunits
17	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 4.1.2.45 - trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

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2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate

Sphingobium xenophagum

698696

Hg2+

Sphingomonas paucimobilis

1 mM, 40% inhibition of fHBP HA B

698644

NEM

Sphingomonas paucimobilis

1 mM, 30 min, 25°C, 35% inhibition of fHBP HA B, more than 85% of the initial activity of fHBP HA A remains

698644

p-chloromercuribenzoate

Sphingobium xenophagum

enzyme is partially reactivated by addition of dithiothreitol

698696

PCMB

Sphingomonas paucimobilis

1 mM, 30 min, 25°C, complete inhibition of fHBP HA B, more than 85% of the initial activity of fHBP HA A remains

698644

Salicylaldehyde

Sphingobium xenophagum

698696

sodium borhydride

Sphingobium xenophagum

698696

additional information

3 entries