4.1.2.45: trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

This is an abbreviated version!
For detailed information about trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, go to the full flat file.

Reaction

Synonyms

2'-hydroxybenzalpyruvate aldolase, fHBP HA A, fHBP HA B, nsaE, o-tHBPA hydratase-aldolase, tHBP-HA, tHBPA hydratase-aldolase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

ECTree

     4 Lyases

         4.1 Carbon-carbon lyases

             4.1.2 Aldehyde-lyases

                4.1.2.45 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

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Results	in table
20	AA Sequence
3	Cloned(Commentary)
1	Cofactor
1	General Stability
10	Inhibitors
1	Ki Value [mM]
8	KM Value [mM]
8	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
28	Organism
5	Pathway
2	PDB ID
3	pH Optimum
4	pH Range
3	pH Stability
3	pI Value
4	Purification (Commentary)
1	Reaction
2	Reaction Type
18	Reference
4	Specific Activity [micromol/min/mg]
76	Substrates and Products (Substrate)
9	Subunits
17	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Range [°C]
3	Temperature Stability [°C]

Natural Substrates Products

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Natural Substrates Products on EC 4.1.2.45 - trans-o-hydroxybenzylidenepyruvate hydratase-aldolase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O

salicylaldehyde + pyruvate

4 entries

(E)-2'-hydroxybenzylidenepyruvate + H2O

salicylaldehyde + pyruvate

2 entries

(E)-2'-hydroxybenzylidenepyruvate + O2

salicylaldehyde + pyruvate

Pseudomonas sp.

-

naphthalene metabolism

696061

-

-

?

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O

salicylaldehyde + pyruvate

Celeribacter indicus

-

-

747591

-

-

?

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O

salicylaldehyde + pyruvate

Celeribacter indicus P73T

-

-

747591

-

-

?

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O

salicylaldehyde + pyruvate

Sphingobium xenophagum

-

this reaction is part of the degradative pathways for naphthalene and naphthalenesulfonates by bacteria

698696

-

-

?

(3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate + H2O

salicylaldehyde + pyruvate

Sphingobium xenophagum BN6

-

this reaction is part of the degradative pathways for naphthalene and naphthalenesulfonates by bacteria

698696

-

-

?

(E)-2'-hydroxybenzylidenepyruvate + H2O

salicylaldehyde + pyruvate

Sphingobium xenophagum

-

involved in metabolism of naphthalene to salicylate

699353

-

-

?

(E)-2'-hydroxybenzylidenepyruvate + H2O

salicylaldehyde + pyruvate

Sphingobium xenophagum BN6

-

involved in metabolism of naphthalene to salicylate

699353

-

-

?