3.6.1.58: 8-oxo-dGDP phosphatase
This is an abbreviated version!
For detailed information about 8-oxo-dGDP phosphatase, go to the full flat file.
Reaction
Synonyms
MTH3, MutT homologue 3, NDX-1, NUDT, NUDT5
ECTree
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Cloned
Cloned on EC 3.6.1.58 - 8-oxo-dGDP phosphatase
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the increase in the production of erroneous proteins by oxidative damage is 28fold over the wild-type cells in Escherichia coli mutT deficient cells. By the expression of NUDT5 in the cells, it is reduced to 1.4fold
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when NUDT5 is expressed in Escherichia coli mutT-cells as a His-tagged protein, the increased frequency of spontaneous mutations is decreased to normal levels