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3.6.1.54: UDP-2,3-diacylglucosamine diphosphatase

This is an abbreviated version!
For detailed information about UDP-2,3-diacylglucosamine diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.54

Reaction

a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine
+
H2O
=
a lipid X
+
UMP

Synonyms

LpxH, LpxI, UDP-2, 3-diacylglucosamine hydrolase, UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-beta-D-glucosaminyl 1-phosphate phosphohydrolase, UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine pyrophosphatase, UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate phosphohydrolase, UDP-diacylglucosamine pyrophosphatase, UDP-diacylglucosamine pyrophosphohydrase, UDP-diacylglucosamine pyrophosphohydrolase, YbbF

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase

Substrates Products

Substrates Products on EC 3.6.1.54 - UDP-2,3-diacylglucosamine diphosphatase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
UDP-2,3-bis((3R)-3-hydroxymyristoyl)alpha-D-glucosamine + H2O
2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP
show the reaction diagram
UDP-2,3-diacylglucosamine + H2O
2,3-diacylglucosamine 1-phosphate + UMP
show the reaction diagram
UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine + H2O
2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate + UMP
show the reaction diagram
UDP-N2,O3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine + H2O
N2,O3-bis((3R)-3-hydroxymyristoyl)-alpha-D-glucosamine 1-phosphate + UMP
show the reaction diagram
strict requirement for a diacylated substrate. LpxH hydrolysis incorporates H218O into UMP by catalyzing the attack of water on the alpha-phosphorus atom of UDP-2,3-diacylglucosamine
-
-
?
additional information
?
-