3.6.1.54: UDP-2,3-diacylglucosamine diphosphatase

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For detailed information about UDP-2,3-diacylglucosamine diphosphatase, go to the full flat file.

Word Map on EC 3.6.1.54

3.6.1.54

lipopolysaccharide

pyrophosphate

influenzae

haemophilus

ump

phosphoesterase

calcineurin-like

leaflet

piperazine

sulfonyl

Reaction

a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine

Synonyms

LpxH, LpxI, UDP-2, 3-diacylglucosamine hydrolase, UDP-2,3-bis[(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine 2,3-bis[(3R)-3-hydroxymyristoyl]-beta-D-glucosaminyl 1-phosphate phosphohydrolase, UDP-2,3-diacylglucosamine hydrolase, UDP-2,3-diacylglucosamine pyrophosphatase, UDP-2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine 2-N,3-O-bis[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosaminyl 1-phosphate phosphohydrolase, UDP-diacylglucosamine pyrophosphatase, UDP-diacylglucosamine pyrophosphohydrase, UDP-diacylglucosamine pyrophosphohydrolase, YbbF

ECTree

3 Hydrolases

3.6 Acting on acid anhydrides

3.6.1 In phosphorus-containing anhydrides

3.6.1.54 UDP-2,3-diacylglucosamine diphosphatase

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Results	in table
3	Activating Compound
10236	AA Sequence
1	CAS Registry Number
9	Cloned(Commentary)
3	Crystallization (Commentary)
11	General Information
2	IC50 Value
19	Inhibitors
3	KM Value [mM]
2	Localization
10	Metals/Ions
1	Molecular Weight [Da]
10	Natural Substrates/ Products (Substrates)
2	Organic Solvent Stability
20	Organism
11	Pathway
18	PDB ID
3	pH Optimum
1	pH Range
17	Protein Variants
6	Purification (Commentary)
1	Reaction
15	Reference
4	Specific Activity [micromol/min/mg]
18	Substrates and Products (Substrate)
1	Subunits
36	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Cloned

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Cloned on EC 3.6.1.54 - UDP-2,3-diacylglucosamine diphosphatase

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2 entries

expressed in E. coli strain BL21(DE3) and Bordetella pertussis strain B213

Neisseria meningitidis

757234

expressed in Escherichia coli BL21 (DE3) cells

Azotobacter vinelandii

C1DHE3

720278

expressed in Escherichia coli BL21(DE3) cells

2 entries

expressed in Escherichia coli BL21(DE3)Star cells

Escherichia coli

755698

expressed in lpxh-deficient Escherichia coli CcI 21b cells

Caulobacter vibrioides

A0A0H3C8Q1

718879

lpxH overexpression is toxic to cells

Escherichia coli

P43341

698720