3.5.4.37: double-stranded RNA adenine deaminase
This is an abbreviated version!
For detailed information about double-stranded RNA adenine deaminase, go to the full flat file.
Word Map on EC 3.5.4.37
-
3.5.4.37
-
inosine
-
a-to-i
-
deaminases
-
deamination
-
adenosine-to-inosine
-
hereditaria
-
rna-editing
-
pre-mrnas
-
dyschromatosis
-
symmetrica
-
z-dna
-
duplex
-
ampa
-
left-handed
-
unedited
-
glur-b
-
recoding
-
site-selective
-
macules
-
interferon-inducible
-
mda5
-
hypopigmented
-
ifn-inducible
-
dsrbds
-
interferon-stimulated
-
ca2+-permeable
-
5-ht2cr
-
dicer
-
samhd1
-
genodermatosis
-
rig-i
-
hypermutation
-
ifn-stimulated
-
pigmentary
-
interferonopathy
-
autoinflammatory
-
medicine
-
inosine-containing
-
dsrna-binding
-
drug development
-
protein-rna
-
antigenome
- 3.5.4.37
- inosine
-
a-to-i
- deaminases
-
deamination
-
adenosine-to-inosine
-
hereditaria
-
rna-editing
- pre-mrnas
-
dyschromatosis
-
symmetrica
- z-dna
- duplex
- ampa
-
left-handed
-
unedited
-
glur-b
-
recoding
-
site-selective
-
macules
-
interferon-inducible
- mda5
-
hypopigmented
-
ifn-inducible
-
dsrbds
-
interferon-stimulated
-
ca2+-permeable
-
5-ht2cr
- dicer
- samhd1
-
genodermatosis
- rig-i
-
hypermutation
-
ifn-stimulated
-
pigmentary
-
interferonopathy
-
autoinflammatory
- medicine
-
inosine-containing
-
dsrna-binding
- drug development
-
protein-rna
-
antigenome
Reaction
Synonyms
ADAR, ADAR1, ADAR1L, ADAR1S, ADAR2, ADAR2 deaminase, adenosine deaminase acting on RNA 1, adenosine deaminase acting on RNA-1, APOBEC1, bADAR1a, CiADAR1, dADAR, double-stranded RNA adenosine deaminase, double-stranded RNA-specific adenosine deaminase, double-stranded RNA-specific adenosine deaminase 1, double-stranded-RNA-specific adenosine deaminase 1, DRADA1, dsRAD, dsRNA adenosine deaminase, hADAR1, hADAR1a, hADAR2, hADAR2-D
ECTree
Advanced search results
Application
Application on EC 3.5.4.37 - double-stranded RNA adenine deaminase
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
drug development
medicine
ADAR1 is a potential therapeutic target in a subset of cancers
drug development
the enzyme (ADAR1) promotes the Zika virus replication by inhibiting the activation of protein kinase PKR. The enzyme can be a potential target of antiviral drugs
ADAR2 is a promising target for an anti-tumoral strategy, since ADAR2 alone can simultaneously modulate more than one miRNA and cellular pathway altered in cancer cells
medicine
enzyme (ADAR1) expression is an independent predictor of tumor recurrence. Small molecule inhibition of focal adhesion kinase activity may be a potential therapeutic strategy for the treatment of lung adenocarcinoma with high ADAR1 expression
medicine
the levels of RNA editing by ADAR1 can serve as new tools for diagnosis in cancer stem cell-related illnesses. In situations where ADAR1 overexpression contributes to disease progression, as in several cancers, or where ADAR1 interacts with other proteins in editing-independent manners, inhibition of ADAR1 could potentially be another strategy in treatment