3.5.1.121: protein N-terminal asparagine amidohydrolase

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For detailed information about protein N-terminal asparagine amidohydrolase, go to the full flat file.

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Synonyms

amidohydrolase for N-terminal asparagine, N-terminal amidase, N-terminal asparagine amidohydrolase, Nt-amidase, NTA1, NTAN1, NTAN1 amidase, NTAN1p amidase, NtN-amidase, PNAD, protein NH2-terminal asparagine deamidase, yNta1

ECTree

     3 Hydrolases

         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds

             3.5.1 In linear amides

                3.5.1.121 protein N-terminal asparagine amidohydrolase

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Results	in table
16	AA Sequence
5	Cloned(Commentary)
9	Disease/ Diagnostics
4	Expression
23	General Information
15	Inhibitors
2	KM Value [mM]
5	Localization
3	Molecular Weight [Da]
12	Natural Substrates/ Products (Substrates)
11	Organism
1	Pathway
2	pH Optimum
1	pI Value
10	Protein Variants
2	Purification (Commentary)
1	Reaction
11	Reference
25	Source Tissue
24	Substrates and Products (Substrate)
5	Subunits
25	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

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Cloned on EC 3.5.1.121 - protein N-terminal asparagine amidohydrolase

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

gene Ntan1 gene is located in the proximal region of mouse chromosome 16 and contains 10 exons ranging from 54 to 177 base pairs in length, recombinant expression of mouse NtN-amidase in Saccharomyces cerevisiae nta1DELTA enzyme-deficient strain

Saccharomyces cerevisiae

P40354

740657

gene Ntan1, chromosomal localization and expression analysis, recombinant expression of N-terminally GFP-tagged 65-kDa in NTAN1pmouse 3T3 cells

Mus musculus

Q64311

740991

gene Ntan1, DNA and amino acid sequence determination and analysis, Ntan1 promoter identification, chromosome mapping of gene Ntan1 reveals that Ntan1 is located in the proximal region of mouse chromosome 16, the gene is located in the proximal region of mouse chromosome 16 and contains 10 exons ranging from 54 to 177 base pairs in length, recombinant expression of full-length mouse NtN-amidase in Saccharomyces cerevisiae nta1DELTA enzyme-deficient strain

Mus musculus

Q64311

740657

gene NTAN1, phylogenetic analysis, recombinant expression of N-terminally His6-tagged wild-type and mutant enzymes with a C-terminal strepII-tag or a FLAG-strepII tandem affinity tag in Escherichia coli strain BL21(DE3), method improvement

Homo sapiens

Q96AB6

740050

gene Ntan1, rat Ntan1 promoter (-1361 to +99) is prepared from rat genomic DNA by PCR, sequence comparisons, overexpression of Ntan1 using recombinant Ntan1 adenovirus vector resulting in a marked decrease in the MAP2 protein expression in hippocampal neurons

Rattus norvegicus

-

740888