3.4.99.B2: D-aspartyl endopeptidase
This is an abbreviated version!
For detailed information about D-aspartyl endopeptidase, go to the full flat file.
Word Map on EC 3.4.99.B2
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3.4.99.B2
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alzheimer
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cataracts
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noxious
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d-aspartate
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misfolding
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proteasome
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aging-related
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arteriosclerosis
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lactacystin-sensitive
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multi-complex
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racemized
-
prion
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paenibacillus
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d-isomers
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lactacystin
-
elegans
-
analysis
- 3.4.99.B2
- alzheimer
-
cataracts
-
noxious
- d-aspartate
-
misfolding
- proteasome
-
aging-related
-
arteriosclerosis
-
lactacystin-sensitive
-
multi-complex
-
racemized
- prion
- paenibacillus
-
d-isomers
- lactacystin
- elegans
- analysis
Reaction
paenidases specifically recognize internal D-Asp residues and hydrolyze them on the COOH side =
Synonyms
D-aspartyl endopeptidase, DAEP, paenidase
ECTree
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KM Value
KM Value on EC 3.4.99.B2 - D-aspartyl endopeptidase
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0.12
succinyl-D-Asp-alpha-4-methylcoumaryl-7-amide
-
pH 8,5, 37°C
0.14
mutant H276A, pH 7.0, 37°C
0.97
succinyl-D-Asp-7-amido-4-methylcoumarin
wild-type, pH 7.0, 37°C