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3.4.24.B37: mutalysin II

This is an abbreviated version!
For detailed information about mutalysin II, go to the full flat file.

Word Map on EC 3.4.24.B37

Reaction

The enzyme cleaves the Ala14-/-Leu15 bond of insulin B-chain very rapidly and the Phe24-/-Phe25, His10-/-Leu11 and His5-/-Leu6 bonds additional information slowly =

Synonyms

haemorrhagic factor 2, hemorrhagic factor II, LHF-II, LHFII, snake venom metalloproteinase hemorrhagic factor 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B37 mutalysin II

Inhibitors

Inhibitors on EC 3.4.24.B37 - mutalysin II

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1,10-phenanthroline
hemorrhagic as well as the proteinase activity is inhibited
EGTA
hemorrhagic as well as the proteinase activity is inhibited
human alpha-2-macroglobulin
activity with dimethylcasein as substrate is completely inhibited, inhibition of of fibrin(ogen) digestion
-
rabbit antibody to mutalysin II
activity with dimethylcasein as substrate is completely inhibited, inhibition of of fibrin(ogen) digestion
-