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3.4.24.B37: mutalysin II

This is an abbreviated version!
For detailed information about mutalysin II, go to the full flat file.

Word Map on EC 3.4.24.B37

Reaction

The enzyme cleaves the Ala14-/-Leu15 bond of insulin B-chain very rapidly and the Phe24-/-Phe25, His10-/-Leu11 and His5-/-Leu6 bonds additional information slowly =

Synonyms

haemorrhagic factor 2, hemorrhagic factor II, LHF-II, LHFII, snake venom metalloproteinase hemorrhagic factor 2

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.24 Metalloendopeptidases
                3.4.24.B37 mutalysin II

Reference

Reference on EC 3.4.24.B37 - mutalysin II

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Agero, U.; Arantes, R.M.; Lacerda-Queiroz, N.; Mesquita, O.N.; Magalhaes, A.; Sanchez, E.F.; Carvalho-Tavares, J.
Effect of mutalysin II on vascular recanalization after thrombosis induction in the ear of the hairless mice model
Toxicon
50
698-706
2007
Lachesis muta muta (P22796), Lachesis muta muta
Manually annotated by BRENDA team
Sanchez, E.F.; Magalhes, A.; Mandelbaum, F.R.; Diniz, C.R.
Purification and characterization of the hemorrhagic factor II from the venom of the Bushmaster snake (Lachesis muta muta)
Biochim. Biophys. Acta
1074
347-356
1991
Lachesis muta muta (P22796), Lachesis muta muta
Manually annotated by BRENDA team
Souza, C.T.; Moura, M.B.; Magalhaes, A.; Heneine, L.G.; Olortegui, C.C.; Diniz, C.R.; Sanchez, E.F.
Inhibition of mutalysin II, a metalloproteinase from bushmaster snake venom by human alpha2-macroglobulin and rabbit immunoglobulin
Comp. Biochem. Physiol. B Biochem. Mol. Biol.
130
155-168
2001
Lachesis muta muta (P22796), Lachesis muta muta
Manually annotated by BRENDA team
Sanchez, E.F.; Diniz, C.R.; Richardson, M.
The complete amino acid sequence of the haemorrhagic factor LHFII, a metalloproteinase isolated from the venom of the bushmaster snake (Lachesis muta muta)
FEBS Lett.
282
178-182
1991
Lachesis muta muta (P22796), Lachesis muta muta
Manually annotated by BRENDA team
Sanchez, E.F.; Cordeiro, M.N.; De Oliveira, E.B.; Juliano, L.; Prado, E.S.; Diniz, C.R.
Proteolytic specificity of two hemorrhagic factors, LHF-I and LHF-II, isolated from the venom of the bushmaster snake (Lachesis muta muta)
Toxicon
33
1061-1069
1991
Lachesis muta muta (P22796), Lachesis muta muta
Manually annotated by BRENDA team