3.4.24.B37: mutalysin II
This is an abbreviated version!
For detailed information about mutalysin II, go to the full flat file.
Word Map on EC 3.4.24.B37
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3.4.24.B37
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lachesis
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bushmaster
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metalloproteinases
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fibrinogen
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dimethylcasein
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fibrin
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proteinases
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immunodiffusion
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endopeptidase
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thrombolytic
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intravital
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bothrops
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alpha2-m
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alpha-chain
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fibrinogenolytic
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fibrinolytic
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alpha2-macroglobulin
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pmsf
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clot
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medicine
- 3.4.24.B37
-
lachesis
- bushmaster
- metalloproteinases
- fibrinogen
- dimethylcasein
- fibrin
- proteinases
-
immunodiffusion
- endopeptidase
-
thrombolytic
-
intravital
- bothrops
-
alpha2-m
- alpha-chain
-
fibrinogenolytic
-
fibrinolytic
- alpha2-macroglobulin
- pmsf
- clot
- medicine
Reaction
The enzyme cleaves the Ala14-/-Leu15 bond of insulin B-chain very rapidly and the Phe24-/-Phe25, His10-/-Leu11 and His5-/-Leu6 bonds additional information slowly =
Synonyms
haemorrhagic factor 2, hemorrhagic factor II, LHF-II, LHFII, snake venom metalloproteinase hemorrhagic factor 2
ECTree
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Substrates Products
Substrates Products on EC 3.4.24.B37 - mutalysin II
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REACTION DIAGRAM
2-aminobenzoyl-Pro-Leu-Gly-Leu-Leu-Gly-Arg-N-(2,4-dinitrophenyl)ethylenediamine + H2O
2-aminobenzoyl-Pro-Leu-Gly-Leu + Leu-Gly-Arg-N-(2,4-dinitrophenyl)ethylenediamine
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?
Bovine insulin B-chain + H2O
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the enzyme cleaves the Ala14-/-Leu15 bond of insulin B-chain very rapidly and the Phe24-/-Phe25, His10-/-Leu11 and His5-/-Leu6 bonds more slowly
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-
?
fibrinogen alpha-chain + H2O
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the enzyme hydrolyzes selectively the alpha-chain of fibrinogen, leaving the beta- and gamma-chains unaffected
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?