3.4.23.B5: murine leukemia virus protease

This is an abbreviated version!
For detailed information about murine leukemia virus protease, go to the full flat file.

Reaction

processing of viral polyprotein. The retroviral protease is essential for virus replication, by processing of viral Gag and Gag-Pol polyproteins =

Synonyms

MLV PR, MLV protease, MLV retropepsin, MMLV protease, Mo-MuLV PR, Mo-MuLV protease, Moloney MLV retropepsin, Moloney murine leukemia virus protease, Moloney murine leukemia virus retropepsin, More, MuLV 4070A, MuLV proteinase, murine leukemia virus protease, viral protease, vPR

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.B5 murine leukemia virus protease

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Results	in table
2	AA Sequence
1	Application
1	CAS Registry Number
9	Cloned(Commentary)
2	Crystallization (Commentary)
2	IC50 Value
19	Inhibitors
1	kcat/KM [mM/s]
12	Ki Value [mM]
94	KM Value [mM]
2	Metals/Ions
4	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
20	Organism
5	pH Optimum
1	pH Range
1	Posttranslational Modification
24	Protein Variants
5	Purification (Commentary)
3	Reaction
1	Reaction Type
20	Reference
2	Specific Activity [micromol/min/mg]
166	Substrates and Products (Substrate)
3	Subunits
19	Synonyms
4	Temperature Optimum [°C]
96	Turnover Number [1/s]

Sequence

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Sequence on EC 3.4.23.B5 - murine leukemia virus protease

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UNIPROT

ENTRY NAME

ORGANISM

NO. OF AA

NO. OF TRANSM. HELICES

MOLECULAR WEIGHT[Da]

SOURCE

SEQUENCE

LOCALIZATION PREDICTIONThe reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable).

A1Z651 pBLAST

POL_XMRV6

Xenotropic MuLV-related virus (isolate VP62)

1733

0

193862

Swiss-Prot

Show Sequence

-

P03355 pBLAST

POL_MLVMS

Moloney murine leukemia virus (isolate Shinnick)

1738

0

194912

Swiss-Prot

Show Sequence

other Location (Reliability: 4)

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