3.4.23.23: Mucorpepsin

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For detailed information about Mucorpepsin, go to the full flat file.

Reaction

Hydrolysis of proteins, favouring hydrophobic residues at P1 and P1'. Clots milk. Does not accept Lys at P1, and hence does not activate trypsinogen =

Synonyms

acid proteinase, aspartic protease, Aspartic proteinase, aspartyl proteinase, EC 3.4.23.6, EC 3.4.4.17, fibrinolytic enzyme, Fromase 100, Fromase 46TL, MCAP, MMP, MPR, Mucor acid protease, Mucor acid proteinase, Mucor aspartic proteinase, Mucor miehei aspartic protease, Mucor miehei aspartic proteinase, Mucor miehei rennin, Mucor pusillus emporase, Mucor pusillus pepsin, Mucor pusillus rennin, Mucor rennin, Proteinase, Mucor aspartic, R. pusillus pepsin, rennin, RMP

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.23 Aspartic endopeptidases

                3.4.23.23 Mucorpepsin

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Results	in table
6	AA Sequence
4	Application
1	CAS Registry Number
5	Cloned(Commentary)
7	Crystallization (Commentary)
1	General Stability
71	Inhibitors
7	kcat/KM [mM/s]
17	KM Value [mM]
4	Localization
13	Metals/Ions
22	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
74	Organism
4	Oxidation Stability
7	PDB ID
34	pH Optimum
4	pH Range
9	pH Stability
9	pI Value
13	Posttranslational Modification
16	Protein Variants
17	Purification (Commentary)
1	Reaction
1	Reaction Type
74	Reference
3	Source Tissue
6	Specific Activity [micromol/min/mg]
137	Substrates and Products (Substrate)
22	Subunits
75	Synonyms
19	Temperature Optimum [°C]
3	Temperature Range [°C]
15	Temperature Stability [°C]
11	Turnover Number [1/s]

Cloned

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Cloned on EC 3.4.23.23 - Mucorpepsin

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CLONED (Commentary)

ORGANISM

UNIPROT

LITERATURE

aspartic proteinase gene expressed in Pichia pastoris

Rhizomucor pusillus

-

650661

expressed in Pichia pastoris

Mucor circinelloides

U5HT00

752456

expressed in Pichia pastoris GS115 cells

Rhizomucor pusillus

-

754970

in Escherichia coli

Rhizomucor miehei

-

30646

Mucor pusillus gene expressed in Saccharomyces cerevisiae

Rhizomucor pusillus

-

30644