3.4.22.6: chymopapain

This is an abbreviated version, for detailed information about chymopapain, go to the full flat file.

Reaction

Similar to that of papain =

Synonyms

Chymopapain, chymopapain A, chymopapain B, chymopapain isoform II, chymopapain isoform III, chymopapain isoform IV, Chymopapain S, EC 3.4.4.11, More, papaya proteinase II, PPII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.6 chymopapain

pH Optimum

pH Optimum on EC 3.4.22.6 - chymopapain

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
4.91
-
assay at. Chymopapain shows the best activity and enantioselectivity in the presence of phosphate buffer (pH 4.91, buffer/MeCN:0.12, v/v), which give the product in yield of 45% with 72:28 (anti/syn ratio) and 78% ee (for anti isomer)
5.5 - 8
-
benzoyl-L-argininamide
6.2
-
assay at
7 - 9
-
casein digestion
7
-
hemoglobin digestion
7.4
-
assay at
additional information
-
pH value of the reaction medium plays a significant role in maintaining the stability and catalytic activity of the enzyme