3.4.22.6: chymopapain

This is an abbreviated version, for detailed information about chymopapain, go to the full flat file.

Reaction

Similar to that of papain =

Synonyms

Chymopapain, chymopapain A, chymopapain B, chymopapain isoform II, chymopapain isoform III, chymopapain isoform IV, Chymopapain S, EC 3.4.4.11, More, papaya proteinase II, PPII

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.6 chymopapain

Substrates Products

Substrates Products on EC 3.4.22.6 - chymopapain

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2,4-dichlorocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 43%, 80:20 anti/syn, ee (anti): 81%
-
-
?
2,6-dichlorocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 39%, 99:01 anti/syn, ee (anti): 58%
-
-
?
2-chlorocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 30%, 86:14 anti/syn, ee (anti): 79%
-
-
?
2-nitrocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 24%, 87:13 anti/syn, ee (anti): 82%
-
-
?
3-chlorocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 32%, 65:35 anti/syn, ee (anti): 93%
-
-
?
3-nitrocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 41%, 87:13 anti/syn, ee (anti): 86%
-
-
?
4-bromocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 29%, 81:19 anti/syn, ee (anti): 84%
-
-
?
4-chlorocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 47%, 69:31 anti/syn, ee (anti): 75%
-
-
?
4-cyanobenzaldehyde + cyclohexanone
4-[hydroxy(2-oxocyclohexyl)methyl]benzonitrile
show the reaction diagram
4-cyanoclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 60%, 72:28 anti/syn, ee (anti): 76%
-
-
?
4-methylcyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 23%, 63:37 anti/syn, ee (anti): 96%
-
-
?
4-nitrocyclohexan-1-one + acetaldehyde
?
show the reaction diagram
-
yield: 12%, ee (anti): 14%
-
-
?
4-nitrocyclohexan-1-one + cycloheptanone
?
show the reaction diagram
-
yield: 19%, 47:53 anti/syn, ee (anti): 26%
-
-
?
4-nitrocyclohexan-1-one + cyclohexanone
?
show the reaction diagram
-
yield: 69%, 63:37 anti/syn, ee (anti): 78%
-
-
?
4-nitrocyclohexan-1-one + cyclopentanone
?
show the reaction diagram
-
yield: 73%, 56:44 anti/syn, ee (anti): 52%
-
-
?
Albumin + H2O
?
show the reaction diagram
-
-
-
-
?
azocasein + H2O
?
show the reaction diagram
-
-
-
-
?
benzoyl-Gly amide + H2O
benzoyl-Gly + NH3
show the reaction diagram
-
weak activity
-
-
?
benzoyl-L-argininamide + H2O
N-benzoyl-Arg + NH3
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Lys phenyl ester + H2O
benzyloxycarbonyl + phenol
show the reaction diagram
-
-
-
-
?
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide
show the reaction diagram
-
-
-
-
?
carbobenzoxy-L-Glu-L-Tyr + H2O
Carbobenzoxy-Glu + Tyr
show the reaction diagram
-
weak activity
-
-
?
casein + H2O
?
show the reaction diagram
-
-
-
-
?
furan-2-carbaldehyde + cyclohexanone
?
show the reaction diagram
-
yield: 16%, 63:37 anti/syn, ee (anti): 61%
-
-
?
Hemoglobin + H2O
?
show the reaction diagram
-
-
-
-
?
L-Leu amide + H2O
Leu + NH3
show the reaction diagram
-
weak activity
-
-
?
L-Leu-L-Tyr + H2O
Leu + Tyr
show the reaction diagram
-
weak activity
-
-
?
methyl red-Abu-Ala-Pro-Val-Lys-Lys(N5-(5-carboxyfluorescein))-NH2 + H2O
methyl red-Abu-Ala-Pro-Val-Lys + Lys(N5-(5-carboxyfluorescein))-NH2
show the reaction diagram
methyl red-Abu-Ser-Ala-Pro-Val-Lys-Ala-Lys(N5-(5-carboxyfluorescein))-NH2 + H2O
methyl red-Abu-Ser-Ala-Pro-Val-Lys + Ala-Lys(N5-(5-carboxyfluorescein))-NH2
show the reaction diagram
-
pH 6.2 or pH 7.4, 10 min, 37C
-
-
?
methyl red-Abu-Ser-Ala-Pro-Val-Lys-Ala-Lys(N6-(5-carboxyfluorescein))-NH2 + H2O
methyl red-Abu-Ser-Ala-Pro-Val-Lys + Ala-Lys(N6-(5-carboxyfluorescein))-NH2
show the reaction diagram
-
FRET 1, fluorescence resonance energy transfer peptide 1
-
-
?
N,N-diBoc-dityrosine-(isoniacid)2 + H2O
N,N-diBoc-dityrosine + 2 isoniacid
show the reaction diagram
-
-
-
-
?
N-acetyl-L-Phe-L-Tyr + H2O
?
show the reaction diagram
-
weak activity
-
-
?
N-alpha-benzoyl-DL-arginine-p-nitroanilide + H2O
N-alpha-benzoyl-DL-arginine + p-nitroaniline
show the reaction diagram
-
-
-
-
?
N-alpha-benzoyl-DL-arginine-para-nitroanilide + H2O
?
show the reaction diagram
-
-
-
-
?
N-alpha-benzoyl-L-arginine ethyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
N-alpha-benzoylphenylalanine-arginine-4-methylcoumarin-7-amide + H2O
?
show the reaction diagram
-
-
-
-
?
N-benzoyl-Arg-4-nitroanilide + H2O
N-benzoyl-Arg + 4-nitroaniline
show the reaction diagram
N-benzoyl-L-Arg ethyl ester + H2O
N-benzoyl-Arg + ethanol
show the reaction diagram
-
-
-
-
?
N-benzyloxycarbonyl-Gly p-nitrophenyl ester + H2O
N-benzyloxycarbonyl-Gly + p-nitrophenol
show the reaction diagram
-
-
-
-
?
N-tosyl-L-Arg methyl ester + H2O
N-tosyl-Arg + methanol
show the reaction diagram
-
-
-
-
?
succinyl-albumin
?
show the reaction diagram
-
-
-
-
?
succinyl-Phe-Arg-p-nitroanilide + H2O
succinyl-Phe-Arg + p-nitroaniline
show the reaction diagram
-
mechanism of action
-
-
?
additional information
?
-